A New Approach Towards the Synthesis of Pseudaminic Acid Analogues
Abstract
The pseudaminic acids are a family of 5,7-diamino-3,5,7,9-tetradeoxynonulosonic acids that are essential components of bacterial polysaccharides and glycoproteins. This paper describes our approach towards the synthesis of analogues of pseudaminic acid, and involves the efficient introduction of the requisite nitrogen functionalities from a readily available precursor.
Journal Title
Organic & Biomolecular Chemistry
Volume
12
Copyright Statement
© 2014 Royal Society of Chemistry. This is the author-manuscript version of this paper. Reproduced in accordance with the copyright policy of the publisher. Please refer to the journal website for access to the definitive, published version.
Subject
Medicinal and biomolecular chemistry
Organic chemistry
Organic chemical synthesis