A New Approach Towards the Synthesis of Pseudaminic Acid Analogues

The pseudaminic acids are a family of 5,7-diamino-3,5,7,9-tetradeoxynonulosonic acids that are essential components of bacterial polysaccharides and glycoproteins. This paper describes our approach towards the synthesis of analogues of pseudaminic acid, and involves the efficient introduction of the requisite nitrogen functionalities from a readily available precursor.The pseudaminic acids are a family of 5,7-diamino-3,5,7,9-tetradeoxynonulosonic acids that are essential components of bacterial polysaccharides and glycoproteins. This paper describes our approach towards the synthesis of analogues of pseudaminic acid, and involves the efficient introduction of the requisite nitrogen functionalities from a readily available precursor.
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Journal Title

Organic & Biomolecular Chemistry

Volume

DOI

https://doi.org/10.1039/C3OB42491J

Copyright Statement

© 2014 Royal Society of Chemistry. This is the author-manuscript version of this paper. Reproduced in accordance with the copyright policy of the publisher. Please refer to the journal website for access to the definitive, published version.

Subject

Medicinal and biomolecular chemistry

Organic chemistry

Organic chemical synthesis

Publication URI

http://hdl.handle.net/10072/62364

Collection

Journal articles