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dc.contributor.authorWaters, Allison M
dc.contributor.authorPeters, Rosie-Mae
dc.contributor.authorForrest, Kylee E
dc.contributor.authorZimmer-Gembeck, Melanie
dc.date.accessioned2018-01-11T01:54:06Z
dc.date.available2018-01-11T01:54:06Z
dc.date.issued2014
dc.date.modified2014-08-18T05:45:22Z
dc.identifier.issn1878-9293
dc.identifier.doi10.1016/j.dcn.2013.10.007
dc.identifier.urihttp://hdl.handle.net/10072/62408
dc.description.abstractMaternal anxiety and depression are significant risk factors for the development of these disorders in offspring. The pathways through which risk is conferred remain unclear. This study examined fear acquisition and extinction in 26 children at high risk for emotional disorders by virtue of maternal psychopathology (n = 14 with a mother with a principal anxiety disorder and n = 12 with a mother with a principal unipolar depressive disorder) and 31 low risk controls using a discriminative Pavlovian conditioning procedure. Participants, aged between 7 and 14 years, completed 16 trials of discriminative conditioning of two geometric figures, with (CS+) and without (CS-) an aversive tone (US), followed by 8 extinction trials (4 נCS+, 4 נCS-). In the context of comparable discriminative conditioning, children of anxious mothers showed larger skin conductance responses during extinction to the CS+ compared to the CS-, and to both CSs from the first to the second block of extinction trials, in comparison with low risk controls. Compared to low risk controls, children of depressed mothers showed smaller skin conductance responses to the CS+ than the CS- during acquisition. These findings suggest distinct psychophysiological premorbid risk markers in offspring of anxious and depressed mothers.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.language.isoeng
dc.publisherElsevier
dc.publisher.placeUnited Kingdom
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom30
dc.relation.ispartofpageto42
dc.relation.ispartofjournalDevelopmental Cognitive Neuroscience
dc.relation.ispartofvolume7
dc.rights.retentionY
dc.subject.fieldofresearchClinical sciences
dc.subject.fieldofresearchNeurosciences
dc.subject.fieldofresearchCognitive and computational psychology
dc.subject.fieldofresearchBiological psychology
dc.subject.fieldofresearchClinical and health psychology
dc.subject.fieldofresearchcode3202
dc.subject.fieldofresearchcode3209
dc.subject.fieldofresearchcode5204
dc.subject.fieldofresearchcode5202
dc.subject.fieldofresearchcode5203
dc.titleFear acquisition and extinction in offspring of mothers with anxiety and depressive disorders
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
dcterms.licensehttps://creativecommons.org/licenses/by-nc-nd/3.0/
dc.description.versionVersion of Record (VoR)
gro.facultyGriffith Health, School of Applied Psychology
gro.rights.copyright© 2013 The Authors. Published by Elsevier Ltd. Open access under CC BY-NC-ND license.
gro.hasfulltextFull Text
gro.griffith.authorZimmer-Gembeck, Melanie
gro.griffith.authorWaters, Allison M.


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