dc.contributor.author | Karjalainen, T | |
dc.contributor.author | Waligora-Dupriet, AJ | |
dc.contributor.author | Cerquetti, M | |
dc.contributor.author | Spigaglia, P | |
dc.contributor.author | Maggioni, A | |
dc.contributor.author | Mauri, P | |
dc.contributor.author | Mastrantonio, P | |
dc.date.accessioned | 2013-06-29 | |
dc.date.accessioned | 2017-03-02T00:45:07Z | |
dc.date.available | 2015-06-01T23:39:06Z | |
dc.date.available | 2017-03-02T00:45:07Z | |
dc.date.issued | 2001 | |
dc.identifier.issn | 0019-9567 | |
dc.identifier.doi | 10.1128/IAI.69.5.3442-3446.2001 | |
dc.identifier.uri | http://hdl.handle.net/10072/62972 | |
dc.description.abstract | The gene slpA, encoding the S-layer precursor protein in the virulent Clostridium difficile strains C253 and 79–685, was identified. The precursor protein carries a C-terminal highly conserved anchoring domain, similar to the one found in the Cwp66 adhesin (previously characterized in strain 79–685), an SLH domain, and a variable N-terminal domain mediating cell adherence. The genes encoding the S-layer precursor proteins and the Cwp66 adhesin are present in a genetic locus carrying 17 open reading frames, 11 of which encode a similar two-domain architecture, likely to include surface-anchored proteins. | |
dc.description.peerreviewed | Yes | |
dc.description.publicationstatus | Yes | |
dc.language | English | |
dc.language.iso | eng | |
dc.publisher | American Society for Microbiology | |
dc.publisher.place | USA | |
dc.relation.ispartofpagefrom | 3442 | |
dc.relation.ispartofpageto | 3446 | |
dc.relation.ispartofissue | 5 | |
dc.relation.ispartofjournal | Infection and Immunity | |
dc.relation.ispartofvolume | 69 | |
dc.subject.fieldofresearch | Biological sciences | |
dc.subject.fieldofresearch | Genomics | |
dc.subject.fieldofresearch | Agricultural, veterinary and food sciences | |
dc.subject.fieldofresearch | Biomedical and clinical sciences | |
dc.subject.fieldofresearchcode | 31 | |
dc.subject.fieldofresearchcode | 310509 | |
dc.subject.fieldofresearchcode | 30 | |
dc.subject.fieldofresearchcode | 32 | |
dc.title | Molecular and Genomic Analysis of Genes Encoding Surface-Anchored Proteins from Clostridium difficile | |
dc.type | Journal article | |
dc.type.description | C1 - Articles | |
dc.type.code | c1x | |
gro.faculty | Faculty of Science, Environment, Engineering and Technology | |
gro.date.issued | 2015-06-01T23:39:06Z | |
gro.hasfulltext | No Full Text | |
gro.griffith.author | Maggioni, Andrea | |