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dc.contributor.authorDashti, Yousef
dc.contributor.authorGrkovic, Tanja
dc.contributor.authorQuinn, Ronald J
dc.date.accessioned2017-05-03T15:59:44Z
dc.date.available2017-05-03T15:59:44Z
dc.date.issued2014
dc.date.modified2014-10-07T23:45:22Z
dc.identifier.issn0265-0568
dc.identifier.doi10.1039/C4NP00021H
dc.identifier.urihttp://hdl.handle.net/10072/63383
dc.description.abstractMycobacterium tuberculosis (Mtb) still remains a deadly pathogen two decades after the announcement of tuberculosis (TB) as a global health emergency by the World Health Organization. In last few years new drug combinations have shown promising potential to significantly shorten TB treatment times. However there are very few new chemical entities being developed to treat this global threat. From January 1990 to December 2012, 949 anti-mycobacterium natural products were reported in the literature. Here we present a perspective based on an analysis of the drug-like properties of the reported anti-mycobacterium natural products in order to assess drug potential.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.language.isoeng
dc.publisherRSC Publications
dc.publisher.placeUnited Kingdom
dc.relation.ispartofstudentpublicationY
dc.relation.ispartofpagefrom990
dc.relation.ispartofpageto998
dc.relation.ispartofissue8
dc.relation.ispartofjournalNatural Product Reports
dc.relation.ispartofvolume31
dc.rights.retentionY
dc.subject.fieldofresearchChemical sciences
dc.subject.fieldofresearchBiologically active molecules
dc.subject.fieldofresearchBiological sciences
dc.subject.fieldofresearchBiomedical and clinical sciences
dc.subject.fieldofresearchcode34
dc.subject.fieldofresearchcode340401
dc.subject.fieldofresearchcode31
dc.subject.fieldofresearchcode32
dc.titlePredicting natural product value, an exploration of anti-TB drug space
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.facultyGriffith Sciences, Griffith Institute for Drug Discovery
gro.hasfulltextNo Full Text
gro.griffith.authorQuinn, Ronald J.


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