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dc.contributor.authorMomeni, Mohammad
dc.contributor.authorHassanshahi, Gholamhossein
dc.contributor.authorArababadi, Mohammad Kazemi
dc.contributor.authorKennedy, Derek
dc.date.accessioned2017-05-03T11:12:44Z
dc.date.available2017-05-03T11:12:44Z
dc.date.issued2014
dc.identifier.issn0301-4851
dc.identifier.doi10.1007/s11033-014-3355-7
dc.identifier.urihttp://hdl.handle.net/10072/63883
dc.description.abstractMicro-RNAs (miRNAs) play key roles in regulating genes of the immune system. The aim of this study was to examine the expression of miR-1, 21 and 125a in the immune cells taken from the peripheral blood of patients suffering from chronic HBV infection (CHB). This cross-sectional study was performed on 60 CHB patients and 60 healthy controls and expression of miR-1, 21 and 125a was evaluated using quantitative Real-Time PCR. The results showed that expression of miR-1, 21 and 125a was significantly increased in CHB patients in comparison to healthy controls. Based on our results it may be concluded that increased expression of miR-1, 21 and 125a is significantly associated with CHB and may play key roles in the induction of impaired immune responses in CHB patients.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.publisherSpringer Netherlands
dc.publisher.placeNetherlands
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom4833
dc.relation.ispartofpageto4837
dc.relation.ispartofissue7
dc.relation.ispartofjournalMolecular Biology Reports
dc.relation.ispartofvolume41
dc.rights.retentionY
dc.subject.fieldofresearchMedical Virology
dc.subject.fieldofresearchBiochemistry and Cell Biology
dc.subject.fieldofresearchcode110804
dc.subject.fieldofresearchcode0601
dc.titleEctopic expression of micro-RNA-1, 21 and 125a in peripheral blood immune cells is associated with chronic HBV infection
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.hasfulltextNo Full Text
gro.griffith.authorKennedy, Derek D.


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