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dc.contributor.authorMomeni, Mohammaden_US
dc.contributor.authorHassanshahi, Gholamhosseinen_US
dc.contributor.authorArababadi, Mohammad Kazemien_US
dc.contributor.authorKennedy, Dereken_US
dc.date.accessioned2017-05-03T11:12:44Z
dc.date.available2017-05-03T11:12:44Z
dc.date.issued2014en_US
dc.identifier.issn03014851en_US
dc.identifier.doi10.1007/s11033-014-3355-7en_US
dc.identifier.urihttp://hdl.handle.net/10072/63883
dc.description.abstractMicro-RNAs (miRNAs) play key roles in regulating genes of the immune system. The aim of this study was to examine the expression of miR-1, 21 and 125a in the immune cells taken from the peripheral blood of patients suffering from chronic HBV infection (CHB). This cross-sectional study was performed on 60 CHB patients and 60 healthy controls and expression of miR-1, 21 and 125a was evaluated using quantitative Real-Time PCR. The results showed that expression of miR-1, 21 and 125a was significantly increased in CHB patients in comparison to healthy controls. Based on our results it may be concluded that increased expression of miR-1, 21 and 125a is significantly associated with CHB and may play key roles in the induction of impaired immune responses in CHB patients.en_US
dc.description.peerreviewedYesen_US
dc.description.publicationstatusYesen_US
dc.languageEnglishen_US
dc.publisherSpringer Netherlandsen_US
dc.publisher.placeNetherlandsen_US
dc.relation.ispartofstudentpublicationNen_US
dc.relation.ispartofpagefrom4833en_US
dc.relation.ispartofpageto4837en_US
dc.relation.ispartofissue7en_US
dc.relation.ispartofjournalMolecular Biology Reportsen_US
dc.relation.ispartofvolume41en_US
dc.rights.retentionYen_US
dc.subject.fieldofresearchMedical Virologyen_US
dc.subject.fieldofresearchcode110804en_US
dc.titleEctopic expression of micro-RNA-1, 21 and 125a in peripheral blood immune cells is associated with chronic HBV infectionen_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Peer Reviewed (HERDC)en_US
dc.type.codeC - Journal Articlesen_US
gro.hasfulltextNo Full Text


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