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dc.contributor.authorBrenu, E.
dc.contributor.authorMcNaughton, L.
dc.contributor.authorMarshall-Gradisnik, S.
dc.date.accessioned2017-05-03T16:13:16Z
dc.date.available2017-05-03T16:13:16Z
dc.date.issued2011
dc.identifier.issn18755607
dc.identifier.doi10.2174/138955711795445907
dc.identifier.urihttp://hdl.handle.net/10072/64719
dc.description.abstractAnabolic androgenic steroids (AAS) are artificial substances, acting through androgen receptors and were primarily developed for the treatment of hypogonadism, tumors, hypercalcemia, hypercalcuria and other chronic diseases. The discovery, in the early 1930s that these substances may have other benefits related to improvement in physique and athletic performance, has encouraged extensive use of these substances by amateur and professional athletes and members of the general public. The range of AAS used can be classified as either endogenous or exogenous. When used for ergogenic or recreational purposes the dosage is more often higher than the recommended dosage, and at supraphysiological levels, AAS can cause a number of serious side effects including liver dysfunction, myocardial infarction and potentially stroke, due to its ability to increase platelet and platelet aggregation. Furthermore, these high dosages may or can affect other physiological systems including the immune system. Hence, this paper reviews the current research on the effects of a number of specific AAS in the immune system. - See more at: http://www.eurekaselect.com/87885/article#sthash.ovR8HtaQ.dpuf
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.language.isoeng
dc.publisherBentham Science Publishers
dc.publisher.placeNetherlands
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom438
dc.relation.ispartofpageto445
dc.relation.ispartofissue5
dc.relation.ispartofjournalMini Reviews in Medicinal Chemistry
dc.relation.ispartofvolume11
dc.rights.retentionN
dc.subject.fieldofresearchCellular Immunology
dc.subject.fieldofresearchMedicinal and Biomolecular Chemistry
dc.subject.fieldofresearchPharmacology and Pharmaceutical Sciences
dc.subject.fieldofresearchcode110704
dc.subject.fieldofresearchcode0304
dc.subject.fieldofresearchcode1115
dc.titleIs there potential immune dysfunction with anabolic androgenic steroid use: A Review
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.hasfulltextNo Full Text
gro.griffith.authorMarshall-Gradisnik, Sonya M.
gro.griffith.authorBrenu, Ekua


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