• myGriffith
    • Staff portal
    • Contact Us⌄
      • Future student enquiries 1800 677 728
      • Current student enquiries 1800 154 055
      • International enquiries +61 7 3735 6425
      • General enquiries 07 3735 7111
      • Online enquiries
      • Staff phonebook
    View Item 
    •   Home
    • Griffith Research Online
    • Journal articles
    • View Item
    • Home
    • Griffith Research Online
    • Journal articles
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

  • All of Griffith Research Online
    • Communities & Collections
    • Authors
    • By Issue Date
    • Titles
  • This Collection
    • Authors
    • By Issue Date
    • Titles
  • Statistics

  • Most Popular Items
  • Statistics by Country
  • Most Popular Authors
  • Support

  • Contact us
  • FAQs
  • Admin login

  • Login
  • β-Chitin hydrogel/nano hydroxyapatite composite scaffolds for tissue engineering applications

    Author(s)
    Sudheesh Kumar, P.
    Srinivasan, Sowmya
    Lakshmanan, Vinoth-Kumar
    Tamura, H.
    Nair, S.
    Jayakumar, R.
    Griffith University Author(s)
    Pandiyan Thodi, Sudheesh Kumar
    Year published
    2011
    Metadata
    Show full item record
    Abstract
    ߭Chitin hydrogel/nano hydroxyapatite (nHAp) nanocomposite scaffolds were prepared by freeze-drying approach from the mixture of ߭chitin hydrogel and nHAp in different concentrations such as 0.5 and 1%, respectively. The prepared nHAp and nanocomposite scaffolds were characterized using various modalities. Porosity, swelling ability, in vitro degradation, protein adsorption and biomineralization of the prepared composite scaffolds were evaluated. The composite scaffolds were found to have 70-80% porosity with well defined interconnected porous structure. The scaffolds also showed a swelling ratio of 15-20, controlled ...
    View more >
    ߭Chitin hydrogel/nano hydroxyapatite (nHAp) nanocomposite scaffolds were prepared by freeze-drying approach from the mixture of ߭chitin hydrogel and nHAp in different concentrations such as 0.5 and 1%, respectively. The prepared nHAp and nanocomposite scaffolds were characterized using various modalities. Porosity, swelling ability, in vitro degradation, protein adsorption and biomineralization of the prepared composite scaffolds were evaluated. The composite scaffolds were found to have 70-80% porosity with well defined interconnected porous structure. The scaffolds also showed a swelling ratio of 15-20, controlled biodegradation of about 30-40% with enhanced protein adsorption. In addition, the cell viability, attachment and proliferation using MG 63, Vero, NIH3T3 and nHDF cells confirmed the cytocompatibility nature of the nanocomposite scaffolds with well improved cell attachment and proliferation. All these results essentially signify that this material can be a potential candidate for bone and wound tissue engineering applications.
    View less >
    Journal Title
    Carbohydrate Polymers
    Volume
    85
    Issue
    3
    DOI
    https://doi.org/10.1016/j.carbpol.2011.03.018
    Subject
    Macromolecular and Materials Chemistry not elsewhere classified
    Organic Chemistry not elsewhere classified
    Macromolecular and Materials Chemistry
    Organic Chemistry
    Food Sciences
    Publication URI
    http://hdl.handle.net/10072/64741
    Collection
    • Journal articles

    Footer

    Disclaimer

    • Privacy policy
    • Copyright matters
    • CRICOS Provider - 00233E
    • TEQSA: PRV12076

    Tagline

    • Gold Coast
    • Logan
    • Brisbane - Queensland, Australia
    First Peoples of Australia
    • Aboriginal
    • Torres Strait Islander