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dc.contributor.authorMadhumathi, K.
dc.contributor.authorSudheesh Kumar, P.
dc.contributor.authorKavya, K.
dc.contributor.authorFuruike, T.
dc.contributor.authorTamura, H.
dc.contributor.authorNair, S.
dc.contributor.authorJayakumara, R.
dc.date.accessioned2017-05-03T12:45:28Z
dc.date.available2017-05-03T12:45:28Z
dc.date.issued2009
dc.identifier.issn01418130
dc.identifier.doi10.1016/j.ijbiomac.2009.06.009
dc.identifier.urihttp://hdl.handle.net/10072/64742
dc.description.abstractBiopolymers like chitin are widely investigated as scaffolds in bone tissue engineering. Its properties like biocompatibility, biodegradability, non-toxicity, wound healing ability, antibacterial activity, hemostatic property, etc., are widely known. However, these materials are not much bioactive. Addition of material like silica can improve the bioactivity and biocompatibility of chitin. In this work, chitin composite scaffolds containing nanosilica were prepared using chitin hydrogel and their bioactivity, swelling ability and cytotoxicity was analyzed in vitro. These scaffolds were found to be bioactive in simulated body fluid (SBF) and biocompatible when tested with MG 63 cell line. These results suggest that chitin/nanosilica composite scaffolds can be useful for bone tissue engineering applications.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.language.isoeng
dc.publisherElsevier
dc.publisher.placeNetherlands
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom289
dc.relation.ispartofpageto292
dc.relation.ispartofissue3
dc.relation.ispartofjournalInternational Journal of Biological Macromolecules
dc.relation.ispartofvolume45
dc.rights.retentionY
dc.subject.fieldofresearchBiochemistry and Cell Biology not elsewhere classified
dc.subject.fieldofresearchBiochemistry and Cell Biology
dc.subject.fieldofresearchcode060199
dc.subject.fieldofresearchcode0601
dc.titleNovel chitin/nanosilica composite scaffolds for bone tissue engineering applications
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.hasfulltextNo Full Text
gro.griffith.authorPandiyan Thodi, Sudheesh Kumar


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