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dc.contributor.authorRadman, M
dc.contributor.authorGolshiri, A
dc.contributor.authorShamsizadeh, A
dc.contributor.authorZainodini, N
dc.contributor.authorBagheri, V
dc.contributor.authorArababadi, MK
dc.contributor.authorKennedy, D
dc.date.accessioned2017-12-18T01:37:30Z
dc.date.available2017-12-18T01:37:30Z
dc.date.issued2015
dc.identifier.issn0301-0546
dc.identifier.doi10.1016/j.aller.2014.04.006
dc.identifier.urihttp://hdl.handle.net/10072/64976
dc.description.abstractAllergic rhinitis is a nasal hypersensitivity and allergic diseases which leads to inflammation of nasal mucosa. Previous investigations revealed that innate immune receptors play a key role in the pathogenesis of inflammatory diseases including allergic diseases. Toll like receptors (TLRs), which are important innate immune receptors, play crucial roles in recognition of foreign antigens, including allergens, and subsequently for the induction of immune responses such as inflammation. There are several controversial reports regarding the roles of TLR4 in the pathogenesis of allergic rhinitis. This review presents current information regarding the roles of TLR4 in the pathogenesis of allergic rhinitis and the plausible mechanisms which lead to the expression and function of TLR4 in this disease
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.language.isoeng
dc.publisherElsevier
dc.publisher.placeSpain
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom1
dc.relation.ispartofpageto5
dc.relation.ispartofjournalAllergologia et Immunopathologia
dc.rights.retentionY
dc.subject.fieldofresearchImmunology
dc.subject.fieldofresearchcode1107
dc.titleToll-like receptor 4 plays significant roles during allergic rhinitis
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
dcterms.licensehttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.description.versionAccepted Manuscript (AM)
gro.description.notepublicThis publication has been entered into Griffith Research Online as an Advanced Online Version.
gro.rights.copyright© 2014 Sociedad Española de Inmunología Clínica y Alergología Pediátrica and Elsevier España S.L. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International Licence (http://creativecommons.org/licenses/by-nc-nd/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, providing that the work is properly cited.
gro.hasfulltextFull Text
gro.griffith.authorKennedy, Derek D.


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