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dc.contributor.authorCao, Qiming
dc.contributor.authorYu, Jimmy
dc.contributor.authorConnell, Des
dc.date.accessioned2017-05-03T12:06:49Z
dc.date.available2017-05-03T12:06:49Z
dc.date.issued2014
dc.identifier.issn1091-5818
dc.identifier.doi10.1177/1091581814557702
dc.identifier.urihttp://hdl.handle.net/10072/65230
dc.description.abstractAllometric scaling between metabolic rate, size, body temperature and other biological traits has found broad applications in ecology, physiology, and particularly in toxicology (e.g. inter-specific extrapolation). It was observed long ago that basal metabolic rate scales with body mass by a power function, whilst the scaling with temperature was recently proposed to be an exponential function. However, there has been increasing debates on the mass scaling exponent whether it should be 2/3, 3/4 or neither, and the exponential temperature scaling relationship was also questioned by many. This work reports three new scaling laws based on thermodynamic principles to characterize the relationship between these four biological traits. Good correlations were found with the new scaling laws, and no universal scaling exponent can be obtained. Results also demonstrated that individual extrapolation models should be built with the new scaling laws to obtain scaling exponent specific to the interested group of species, which can be applied for scaling and extrapolations in many areas.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.language.isoeng
dc.publisherSage
dc.publisher.placeUnited States
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom1
dc.relation.ispartofpageto9
dc.relation.ispartofjournalInternational Journal of Toxicology
dc.rights.retentionY
dc.subject.fieldofresearchAtmospheric composition, chemistry and processes
dc.subject.fieldofresearchEnvironmental engineering not elsewhere classified
dc.subject.fieldofresearchPharmacology and pharmaceutical sciences
dc.subject.fieldofresearchcode370104
dc.subject.fieldofresearchcode401199
dc.subject.fieldofresearchcode3214
dc.titleNew allometric scaling relationships and applications for dose and toxicity extrapolation
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.facultyGriffith Sciences, Griffith School of Environment
gro.hasfulltextNo Full Text
gro.griffith.authorConnell, Des W.
gro.griffith.authorYu, Jimmy J.


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