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  • Effects of probiotic supplementation over 5 months on routine haematology and clinical chemistry measures in healthy active adults

    Author(s)
    Cox, AJ
    West, NP
    Horn, PL
    Lehtinent, MJ
    Koerbin, G
    Pyne, DB
    Lahtinent, SJ
    Fricker, PA
    Cripps, AW
    Griffith University Author(s)
    Cripps, Allan W.
    West, Nic P.
    Cox, Amanda J.
    Year published
    2014
    Metadata
    Show full item record
    Abstract
    Use of probiotic-containing foods and probiotic supplements is increasing; however, few studies document safety and tolerability in conjunction with defined clinical end points. This paper reports the effects of 150 days of supplementation with either a single- (Bifidobacterium animalis subsp. lactis Bl-04) or a double-strain (Lactobacillus acidophilus NCFM and Bifidobacterium animalis subsp. lactis Bi-07) probiotic on routine haematology and clinical chemistry measures in healthy active adults. Pre- to post-intervention changes in laboratory measures were determined and compared between supplement and placebo groups. Overall ...
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    Use of probiotic-containing foods and probiotic supplements is increasing; however, few studies document safety and tolerability in conjunction with defined clinical end points. This paper reports the effects of 150 days of supplementation with either a single- (Bifidobacterium animalis subsp. lactis Bl-04) or a double-strain (Lactobacillus acidophilus NCFM and Bifidobacterium animalis subsp. lactis Bi-07) probiotic on routine haematology and clinical chemistry measures in healthy active adults. Pre- to post-intervention changes in laboratory measures were determined and compared between supplement and placebo groups. Overall there were few differences in routine haematology and clinical chemistry measures between supplement and placebo groups post-intervention. Exceptions included plasma calcium (P=0.03) and urea (P=0.015); however, observed changes were small and within assay-specific laboratory reference ranges. These data provide evidence supporting the use of these probiotic supplements over a period of 5 months in healthy active adults without obvious safety or tolerability issues.
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    Journal Title
    European Journal of Clinical Nutrition
    DOI
    https://doi.org/10.1038/ejcn.2014.137
    Subject
    Food sciences
    Sports science and exercise
    Nutrition and dietetics
    Nutrition and dietetics not elsewhere classified
    Publication URI
    http://hdl.handle.net/10072/65416
    Collection
    • Journal articles

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