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  • Role of microRNA-34 family in cancer with particular reference to cancer angiogenesis

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    Accepted Manuscript (AM)
    Author(s)
    Maroof, Hamidreza
    Salajegheh, Ali
    Smith, Robert Anthony
    Lam, Alfred King-Yin
    Griffith University Author(s)
    Lam, Alfred K.
    Ariana, Armin S.
    Year published
    2014
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    Abstract
    MicroRNA-34 is involved in pathogenesis in cancer by targeting different tumor-related genes. It could be a biomarker for predicting the prognosis of patients with cancer. In addition, miR-34 is involved in the tumor angiogenesis. Understanding the mechanism of the miR-34 in cancer and tumor angiogenesis will open horizons for development of anti-cancer and anti-angiogenesis drugs.MicroRNA-34 is involved in pathogenesis in cancer by targeting different tumor-related genes. It could be a biomarker for predicting the prognosis of patients with cancer. In addition, miR-34 is involved in the tumor angiogenesis. Understanding the mechanism of the miR-34 in cancer and tumor angiogenesis will open horizons for development of anti-cancer and anti-angiogenesis drugs.
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    Journal Title
    Experimental and Molecular Pathology
    Volume
    97
    Issue
    2
    DOI
    https://doi.org/10.1016/j.yexmp.2014.08.002
    Copyright Statement
    © 2014 Elsevier. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (http://creativecommons.org/licenses/by-nc-nd/4.0/).
    Subject
    Clinical sciences
    Publication URI
    http://hdl.handle.net/10072/65532
    Collection
    • Journal articles

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