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dc.contributor.authorJ. Owen, Daviden_US
dc.contributor.authorThomson, Robinen_US
dc.contributor.authorvon Itzstein, Marken_US
dc.date.accessioned2017-04-24T07:56:26Z
dc.date.available2017-04-24T07:56:26Z
dc.date.issued2002en_US
dc.date.modified2009-10-19T05:22:20Z
dc.identifier.issn00086215en_US
dc.identifier.doi10.1016/S0008-6215(02)00133-7en_AU
dc.identifier.urihttp://hdl.handle.net/10072/6565
dc.description.abstractGalactofuranose sugar units are essential for the production of the cell coat of many pathogenic microorganisms. This sugar is not found in mammals, and so compounds that may interfere with the biosynthetic processing of this sugar unit provide interesting targets for drug design. This paper describes the use of a cyanation reaction for the production of a one-carbon extension of a galactofuranosylic unit at C-1, giving 2,5-anhydro-3,4,6,7-tetra-O-benzoyl--glycero--manno-heptononitrile. A procedure for the efficient hydrolysis of the introduced nitrile group to produce the methyl ester is reported, along with procedures for the synthesis of both the corresponding a,߭unsaturated, and 3-deoxy ester derivatives.en_US
dc.description.peerreviewedYesen_US
dc.description.publicationstatusYesen_AU
dc.languageEnglishen_US
dc.language.isoen_AU
dc.publisherPergamonen_US
dc.publisher.placeUKen_US
dc.publisher.urihttp://www.elsevier.com/wps/find/journaldescription.cws_home/424829/description#descriptionen_AU
dc.relation.ispartofpagefrom2017en_US
dc.relation.ispartofpageto2022en_US
dc.relation.ispartofjournalCarbohydrate Researchen_US
dc.relation.ispartofvolume337en_US
dc.subject.fieldofresearchcode250301en_US
dc.titleA convenient synthesis of C-galactofuranosylic compounds (C-galactofuranosides)en_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Peer Reviewed (HERDC)en_US
dc.type.codeC - Journal Articlesen_US
gro.date.issued2002
gro.hasfulltextNo Full Text


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