Anti-Helicobacter activities of Kakadu Plum and colloidal silver
Author(s)
Cock, Ian Edwin
Whitehouse, Michael
Nesterov, Vladimir
Hancock, Gerald
Year published
2014
Metadata
Show full item recordAbstract
Background. The Kakadu Plum (KP) is wild-harvested in Northern Australia (Nt.WA) and a revered Aboriginal remedy for many ailments. The fruit is rich in ascorbate, other anti-oxidants and contains potent anti-bacterials (1). Colloidal metallic silver (CMS) preparations have shown anti-Helicobacter activity (2).
Procedures. Gastric Helicobacter pylori (HP) infection was assessed with a MetAtron diagnostic monitor (IPP). Volunteers attending a naturopathic clinic took oral treatments with either dried KP extract (1 gm b.i.d.) or CMS (≤0.3 mg Ag b.i.d.) Lunasol™ for five days only. Probability indices for HP infection ...
View more >Background. The Kakadu Plum (KP) is wild-harvested in Northern Australia (Nt.WA) and a revered Aboriginal remedy for many ailments. The fruit is rich in ascorbate, other anti-oxidants and contains potent anti-bacterials (1). Colloidal metallic silver (CMS) preparations have shown anti-Helicobacter activity (2). Procedures. Gastric Helicobacter pylori (HP) infection was assessed with a MetAtron diagnostic monitor (IPP). Volunteers attending a naturopathic clinic took oral treatments with either dried KP extract (1 gm b.i.d.) or CMS (≤0.3 mg Ag b.i.d.) Lunasol™ for five days only. Probability indices for HP infection were determined on days zero, 7, 14 and 28 to assess a) efficacy and b) duration of response post-treatment. [Protocols for clinical studies were approved by an appropriate Human Ethics Committee.] Results: KP extract effectively reduced gastric HP burden >85% within one week. The KP was particularly valuable as second-line treatment in a few subjects (3/17) showing lesser responses (≤40%) to CMS alone. Conclusion: At present, supply constraints and significant harvesting costs may limit the usefulness of KP as a pytotherapy to treat gastric inflammation/ulcers associated with HP. Nevertheless it is a valuable synergist for tandem therapy with other traditional remedies for ulcer disease eg Bismuth, licorice (2).
View less >
View more >Background. The Kakadu Plum (KP) is wild-harvested in Northern Australia (Nt.WA) and a revered Aboriginal remedy for many ailments. The fruit is rich in ascorbate, other anti-oxidants and contains potent anti-bacterials (1). Colloidal metallic silver (CMS) preparations have shown anti-Helicobacter activity (2). Procedures. Gastric Helicobacter pylori (HP) infection was assessed with a MetAtron diagnostic monitor (IPP). Volunteers attending a naturopathic clinic took oral treatments with either dried KP extract (1 gm b.i.d.) or CMS (≤0.3 mg Ag b.i.d.) Lunasol™ for five days only. Probability indices for HP infection were determined on days zero, 7, 14 and 28 to assess a) efficacy and b) duration of response post-treatment. [Protocols for clinical studies were approved by an appropriate Human Ethics Committee.] Results: KP extract effectively reduced gastric HP burden >85% within one week. The KP was particularly valuable as second-line treatment in a few subjects (3/17) showing lesser responses (≤40%) to CMS alone. Conclusion: At present, supply constraints and significant harvesting costs may limit the usefulness of KP as a pytotherapy to treat gastric inflammation/ulcers associated with HP. Nevertheless it is a valuable synergist for tandem therapy with other traditional remedies for ulcer disease eg Bismuth, licorice (2).
View less >
Conference Title
ASCEPT 2014
Publisher URI
Subject
Complementary and Alternative Medicine not elsewhere classified