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dc.contributor.authorCock, Ian Edwin
dc.contributor.authorWhitehouse, Michael
dc.contributor.authorNesterov, Vladimir
dc.contributor.authorHancock, Gerald
dc.date.accessioned2014-12-05
dc.date.accessioned2015-02-23T06:10:24Z
dc.date.accessioned2017-03-02T00:07:03Z
dc.date.available2015-02-23T06:10:24Z
dc.date.available2017-03-02T00:07:03Z
dc.date.issued2014
dc.identifier.urihttp://hdl.handle.net/10072/66371
dc.description.abstractBackground. The Kakadu Plum (KP) is wild-harvested in Northern Australia (Nt.WA) and a revered Aboriginal remedy for many ailments. The fruit is rich in ascorbate, other anti-oxidants and contains potent anti-bacterials (1). Colloidal metallic silver (CMS) preparations have shown anti-Helicobacter activity (2). Procedures. Gastric Helicobacter pylori (HP) infection was assessed with a MetAtron diagnostic monitor (IPP). Volunteers attending a naturopathic clinic took oral treatments with either dried KP extract (1 gm b.i.d.) or CMS (≤0.3 mg Ag b.i.d.) Lunasol™ for five days only. Probability indices for HP infection were determined on days zero, 7, 14 and 28 to assess a) efficacy and b) duration of response post-treatment. [Protocols for clinical studies were approved by an appropriate Human Ethics Committee.] Results: KP extract effectively reduced gastric HP burden >85% within one week. The KP was particularly valuable as second-line treatment in a few subjects (3/17) showing lesser responses (≤40%) to CMS alone. Conclusion: At present, supply constraints and significant harvesting costs may limit the usefulness of KP as a pytotherapy to treat gastric inflammation/ulcers associated with HP. Nevertheless it is a valuable synergist for tandem therapy with other traditional remedies for ulcer disease eg Bismuth, licorice (2).
dc.description.peerreviewedNo
dc.description.publicationstatusYes
dc.publisher.urihttp://www.asceptasm.com/2014-annual-scientific-meeting/
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofconferencenameASCEPT 2014
dc.relation.ispartofconferencetitleASCEPT 2014
dc.relation.ispartofdatefrom2014-12-06
dc.relation.ispartofdateto2014-12-11
dc.relation.ispartoflocationMelbourne Australia
dc.rights.retentionY
dc.subject.fieldofresearchComplementary and Alternative Medicine not elsewhere classified
dc.subject.fieldofresearchcode110499
dc.titleAnti-Helicobacter activities of Kakadu Plum and colloidal silver
dc.typeConference output
dc.type.descriptionE3 - Conferences (Extract Paper)
dc.type.codee3
gro.facultyFaculty of Science, Environment, Engineering and Technology
gro.hasfulltextNo Full Text
gro.griffith.authorCock, Ian E.
gro.griffith.authorWhitehouse, Michael


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