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dc.contributor.authorYoulden, Danny R
dc.contributor.authorBaade, Peter D
dc.contributor.authorValery, Patricia C
dc.contributor.authorWard, Leisa J
dc.contributor.authorGreen, Adele C
dc.contributor.authorAitken, Joanne F
dc.date.accessioned2017-05-03T15:23:47Z
dc.date.available2017-05-03T15:23:47Z
dc.date.issued2011
dc.identifier.issn1055-9965
dc.identifier.doi10.1158/1055-9965.EPI-11-0432
dc.identifier.urihttp://hdl.handle.net/10072/66679
dc.description.abstractBackground: It is not known whether improvements in cancer survival over recent decades have benefited children from different geographic locations equally. This is the first study to produce national survival estimates for childhood cancer in Australia by remoteness of residence and area-based socioeconomic status. Methods: The study utilized population-based data from the Australian Paediatric Cancer Registry for children diagnosed with cancer from 1996 onward who were at risk of mortality between January 2001 and December 2006 (n = 6,289). Remoteness was specified according to the Australian Standard Geographical Classification Remoteness Areas, whereas an index of area disadvantage was obtained from census information. Five-year relative survival estimates were produced by the period method for all cancers and the most common diagnostic groups, with corresponding age-sex adjusted mortality hazard ratios calculated using Poisson regression. Results: Overall, children with cancer from remote/very remote areas had a significantly lower survival rate than their counterparts in major cities (HR = 1.55, 95% CI = 1.08-2.23). Survival was also lower for children with leukemia living in inner regional (HR = 1.52, 95% CI = 1.11-2.08) or outer regional areas (HR = 1.53, 95% CI = 1.03-2.28). There was weak evidence (Pgrad = 0.051) of a trend toward poorer survival by greater area disadvantage for all childhood cancers. Conclusions: Some variation in prognosis by place of residence was present for children with cancer in Australia, particularly among leukemia patients. Impact: Treatment, clinical or area-related factors that contribute to these survival differentials need to be identified.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.format.extent517423 bytes
dc.format.mimetypeapplication/pdf
dc.languageEnglish
dc.language.isoeng
dc.publisherThe American Association for Cancer Research
dc.publisher.placeUnited States
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom1649
dc.relation.ispartofpageto1656
dc.relation.ispartofissue8
dc.relation.ispartofjournalCancer Epidemiology, Biomarkers & Prevention
dc.relation.ispartofvolume20
dc.rights.retentionY
dc.subject.fieldofresearchBiomedical and clinical sciences
dc.subject.fieldofresearchOncology and carcinogenesis not elsewhere classified
dc.subject.fieldofresearchcode32
dc.subject.fieldofresearchcode321199
dc.titleDifferentials in Survival for Childhood Cancer in Australia by Remoteness of Residence and Area Disadvantage
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.rights.copyright© 2011 AACR. This is the author-manuscript version of the paper. Reproduced in accordance with the copyright policy of the publisher. Please refer to the journal link for access to the definitive, published version.
gro.hasfulltextFull Text
gro.griffith.authorBaade, Peter D.
gro.griffith.authorYoulden, Danny R.
gro.griffith.authorAitken, Joanne


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