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dc.contributor.authorOlveda, David U
dc.contributor.authorOlveda, Remigio M
dc.contributor.authorMcManus, Donald P
dc.contributor.authorCai, Pengfei
dc.contributor.authorChau, Thao NP
dc.contributor.authorLam, Alfred K
dc.contributor.authorLi, Yuesheng
dc.contributor.authorHarn, Donald A
dc.contributor.authorVinluan, Marilyn L
dc.contributor.authorRoss, Allen GP
dc.date.accessioned2017-05-03T15:33:34Z
dc.date.available2017-05-03T15:33:34Z
dc.date.issued2014
dc.identifier.issn1201-9712
dc.identifier.doi10.1016/j.ijid.2014.07.009
dc.identifier.urihttp://hdl.handle.net/10072/67120
dc.description.abstractSchistosomiasis is a chronic enteropathogenic disease caused by blood flukes of the genus Schistosoma. The disease afflicts approximately 240 million individuals globally, causing approximately 70 million disability-adjusted life years lost. Chronic infections with morbidity and mortality occur as a result of granuloma formation in the intestine, liver, or in the case of Schistosoma haematobium, the bladder. Various methods are utilized to diagnose and evaluate liver fibrosis due to schistosomiasis. Liver biopsy is still considered the gold standard, but it is invasive. Diagnostic imaging has proven to be an invaluable method in assessing hepatic morbidity in the hospital setting, but has practical limitations in the field. The potential of non-invasive biological markers, serum antibodies, cytokines, and circulating host microRNAs to diagnose hepatic fibrosis is presently undergoing evaluation. This review provides an update on the recent advances made with respect to gastrointestinal disease associated with chronic schistosomiasis.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.format.extent1878566 bytes
dc.format.mimetypeapplication/pdf
dc.languageEnglish
dc.language.isoeng
dc.publisherElsevier
dc.publisher.placeUnited Kingdom
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom193
dc.relation.ispartofpageto203
dc.relation.ispartofjournalInternational Journal of Infectious Diseases
dc.relation.ispartofvolume28
dc.rights.retentionY
dc.subject.fieldofresearchMicrobiology
dc.subject.fieldofresearchMedical microbiology
dc.subject.fieldofresearchMedical parasitology
dc.subject.fieldofresearchClinical sciences
dc.subject.fieldofresearchEpidemiology
dc.subject.fieldofresearchPublic health
dc.subject.fieldofresearchcode3107
dc.subject.fieldofresearchcode3207
dc.subject.fieldofresearchcode320704
dc.subject.fieldofresearchcode3202
dc.subject.fieldofresearchcode4202
dc.subject.fieldofresearchcode4206
dc.titleThe chronic enteropathogenic disease schistosomiasis
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
dcterms.licensehttp://creativecommons.org/licenses/by-nc-nd/3.0/
gro.facultyGriffith Health, School of Medical Science
gro.rights.copyright© The Author(s) 2014. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported (CC BY-NC-ND 3.0) License (http://creativecommons.org/licenses/by-nc-nd/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, providing that the work is properly cited. You may not alter, transform, or build upon this work.
gro.hasfulltextFull Text
gro.griffith.authorLam, Alfred K.
gro.griffith.authorRoss, Allen G.


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