• myGriffith
    • Staff portal
    • Contact Us⌄
      • Future student enquiries 1800 677 728
      • Current student enquiries 1800 154 055
      • International enquiries +61 7 3735 6425
      • General enquiries 07 3735 7111
      • Online enquiries
      • Staff phonebook
    View Item 
    •   Home
    • Griffith Research Online
    • Journal articles
    • View Item
    • Home
    • Griffith Research Online
    • Journal articles
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

  • All of Griffith Research Online
    • Communities & Collections
    • Authors
    • By Issue Date
    • Titles
  • This Collection
    • Authors
    • By Issue Date
    • Titles
  • Statistics

  • Most Popular Items
  • Statistics by Country
  • Most Popular Authors
  • Support

  • Contact us
  • FAQs
  • Admin login

  • Login
  • Utilisation patterns of oxycodone/naloxone combination versus oxycodone alone in a regional hospital

    Author(s)
    Robertson, Kelvin
    Plummer, David
    Ede, Judy
    Scuderi, Carla
    Wenta, Emily
    James, Rosie
    Robertson, Leigh
    Robinson, Niechole
    Stelmaschuk, Marissa
    Perks, Stephen
    Kizur, Karl
    Griffith University Author(s)
    Plummer, David C.
    Year published
    2014
    Metadata
    Show full item record
    Abstract
    Background: Progress in the study and treatment of pain continues as the incidence of pain for patients in hospital remains a significant burden. A novel opioid combination of oxycodone/ naloxone (Targin) was listed on the Queensland Hospital Formulary in March 2012. Previous studies have shown its potential to reduce hospital drug and labour costs due to proven reduction in laxative use. However, it is not known whether the introduction of this combination formula has affected the usage of analgesics and laxatives in our hospital. Aim: To explore usage patterns of oxycodone/naloxone combination (Targin) versus oxycodone ...
    View more >
    Background: Progress in the study and treatment of pain continues as the incidence of pain for patients in hospital remains a significant burden. A novel opioid combination of oxycodone/ naloxone (Targin) was listed on the Queensland Hospital Formulary in March 2012. Previous studies have shown its potential to reduce hospital drug and labour costs due to proven reduction in laxative use. However, it is not known whether the introduction of this combination formula has affected the usage of analgesics and laxatives in our hospital. Aim: To explore usage patterns of oxycodone/naloxone combination (Targin) versus oxycodone alone (Oxycontin) and to determine the cost-effectiveness for the introduction of a new combination formula within the Townsville hospital. Method: Patients were identified and sequentially recruited if eligible according to the inclusion and exclusion criteria. Data was collected prospectively over a two month timeframe using the hospital's existing medication database and reports generated from drug storage and dispensing machines within the facility. Results: Of the 69 patients recruited, 33 and 36 were each prescribed and administered oxycodone/naloxone or oxycodone alone respectively. A difference in case mix was seen with 88% of patients prescribed the combination formula from surgical wards, compared to 33% for the standalone product (X2=21.2, P =<0.0001). A 33% decrease in laxative use was found in the population administered oxycodone/naloxone (X2=7.7, P = 0.005) with a total amount of additional analgesia almost double the comparator single agent group. A higher expenditure per patient for 48 hours treatment was observed with the combination treatment. Conclusion: This study shows that the combination of oxycodone/naloxone results in decreased laxative use and increased additional analgesia. A varied pattern of usage within The Townsville Hospital was observed with potential off-licence practice.
    View less >
    Journal Title
    Australian Pharmacist
    Volume
    7
    Publisher URI
    http://www.psa.org.au/membership/australian-pharmacist
    Copyright Statement
    Self-archiving of the author-manuscript version is not yet supported by this journal. Please refer to the journal link for access to the definitive, published version or contact the authors for more information.
    Subject
    Medical and Health Sciences not elsewhere classified
    Pharmacology and Pharmaceutical Sciences
    Publication URI
    http://hdl.handle.net/10072/67540
    Collection
    • Journal articles

    Footer

    Disclaimer

    • Privacy policy
    • Copyright matters
    • CRICOS Provider - 00233E
    • TEQSA: PRV12076

    Tagline

    • Gold Coast
    • Logan
    • Brisbane - Queensland, Australia
    First Peoples of Australia
    • Aboriginal
    • Torres Strait Islander