Adlumiceine methyl ester, a new alkaloid from Fumaria vaillantii
Author(s)
Iranshahy, Milad
Javidi-Shirazi, Hamideh
Pham, Ngoc B
Quinn, Ronald J
Sadeghian, Hamid
Iranshahi, Mehrdad
Griffith University Author(s)
Year published
2014
Metadata
Show full item recordAbstract
A new alkaloid, adlumiceine methyl ester (1), together with two known alkaloids, parfumine (2) and N-methylhydrastine methyl ester (3), was isolated from aerial parts of Fumaria vaillantii. The structures of compounds were determined by 1D/2D NMR and MS data. All three compounds were tested for cytotoxic activity against PC3 and MCF7 cell lines using Alamar blue assay. The tested compounds showed no significant cytotoxic activity (IC50>50 卩 against PC3 and MCF7 cell lines.A new alkaloid, adlumiceine methyl ester (1), together with two known alkaloids, parfumine (2) and N-methylhydrastine methyl ester (3), was isolated from aerial parts of Fumaria vaillantii. The structures of compounds were determined by 1D/2D NMR and MS data. All three compounds were tested for cytotoxic activity against PC3 and MCF7 cell lines using Alamar blue assay. The tested compounds showed no significant cytotoxic activity (IC50>50 卩 against PC3 and MCF7 cell lines.
View less >
View less >
Journal Title
Journal of Asian Natural Products Research
Volume
16
Issue
12
Subject
Medicinal and biomolecular chemistry not elsewhere classified
Organic chemistry
Plant biology
Pharmacology and pharmaceutical sciences