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  • Adlumiceine methyl ester, a new alkaloid from Fumaria vaillantii

    Author(s)
    Iranshahy, Milad
    Javidi-Shirazi, Hamideh
    Pham, Ngoc B
    Quinn, Ronald J
    Sadeghian, Hamid
    Iranshahi, Mehrdad
    Griffith University Author(s)
    Quinn, Ronald J.
    Year published
    2014
    Metadata
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    Abstract
    A new alkaloid, adlumiceine methyl ester (1), together with two known alkaloids, parfumine (2) and N-methylhydrastine methyl ester (3), was isolated from aerial parts of Fumaria vaillantii. The structures of compounds were determined by 1D/2D NMR and MS data. All three compounds were tested for cytotoxic activity against PC3 and MCF7 cell lines using Alamar blue assay. The tested compounds showed no significant cytotoxic activity (IC50>50 卩 against PC3 and MCF7 cell lines.A new alkaloid, adlumiceine methyl ester (1), together with two known alkaloids, parfumine (2) and N-methylhydrastine methyl ester (3), was isolated from aerial parts of Fumaria vaillantii. The structures of compounds were determined by 1D/2D NMR and MS data. All three compounds were tested for cytotoxic activity against PC3 and MCF7 cell lines using Alamar blue assay. The tested compounds showed no significant cytotoxic activity (IC50>50 卩 against PC3 and MCF7 cell lines.
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    Journal Title
    Journal of Asian Natural Products Research
    Volume
    16
    Issue
    12
    DOI
    https://doi.org/10.1080/10286020.2014.969717
    Subject
    Medicinal and biomolecular chemistry not elsewhere classified
    Organic chemistry
    Plant biology
    Pharmacology and pharmaceutical sciences
    Publication URI
    http://hdl.handle.net/10072/67707
    Collection
    • Journal articles

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