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dc.contributor.authorRashid, Mahmood A
dc.contributor.authorPolash, Md Masbaul Alam
dc.contributor.authorNewton, MA Hakim
dc.contributor.authorHoque, Md Tamjidul
dc.contributor.authorSattar, Abdul
dc.contributor.editorPham, DN
dc.contributor.editorPark, SB
dc.date.accessioned2017-05-03T14:57:11Z
dc.date.available2017-05-03T14:57:11Z
dc.date.issued2014
dc.identifier.isbn978-3-319-13559-5
dc.identifier.issn0302-9743
dc.identifier.doi10.1007/978-3-319-13560-1_12
dc.identifier.urihttp://hdl.handle.net/10072/67848
dc.description.abstractProteins are essentially sequences of amino acids. They adopt specific folded 3-dimensional structures to perform specific tasks. The formation of 3-dimensional structures is largely guided by the constituent amino acids. Therefore, the positional presence of amino acids in a sequence might play important roles during the protein folding process. In this paper, we present a new heuristic derived from the positional patterns of amino acids in a sequence. With the help of a biased tabu tenure, we apply this heuristic within a spiral search algorithm. The spiral search is an efficient algorithm to develop hydrophobic core in a protein structure pulling hydrophobic amino acids towards the core centre in a spiral fashion. On a set of standard benchmark proteins, we experimentally show that applying our new heuristic improves the performance of a spiral search algorithm consistently.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.publisherSpringer
dc.publisher.placeGermany
dc.publisher.urihttp://www.pricai2014.org/
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofconferencename13th Pacific Rim International Conference on Artificial Intelligence (PRICAI)
dc.relation.ispartofconferencetitlePRICAI 2014: TRENDS IN ARTIFICIAL INTELLIGENCE
dc.relation.ispartofdatefrom2014-12-01
dc.relation.ispartofdateto2014-12-05
dc.relation.ispartoflocationGold Coast, AUSTRALIA
dc.relation.ispartofpagefrom143
dc.relation.ispartofpagefrom14 pages
dc.relation.ispartofpageto156
dc.relation.ispartofpageto14 pages
dc.relation.ispartofvolume8862
dc.rights.retentionY
dc.subject.fieldofresearchArtificial intelligence not elsewhere classified
dc.subject.fieldofresearchInformation and computing sciences
dc.subject.fieldofresearchcode460299
dc.subject.fieldofresearchcode46
dc.titleAmino acids pattern-biased spiral search for protein structure prediction
dc.typeConference output
dc.type.descriptionE1 - Conferences
dc.type.codeE - Conference Publications
gro.facultyGriffith Sciences, School of Information and Communication Technology
gro.hasfulltextNo Full Text
gro.griffith.authorSattar, Abdul
gro.griffith.authorRashid, Mahmood A.


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    Contains papers delivered by Griffith authors at national and international conferences.

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