Show simple item record

dc.contributor.authorKasem, Kais Y.
dc.contributor.authorLam, Alfred
dc.date.accessioned2015-02-27
dc.date.accessioned2015-05-15T04:40:07Z
dc.date.accessioned2017-03-01T23:54:53Z
dc.date.available2015-05-15T04:40:07Z
dc.date.available2017-03-01T23:54:53Z
dc.date.issued2014
dc.identifier.isbn0031-3025
dc.identifier.urihttp://hdl.handle.net/10072/68010
dc.description.abstractExtra-adrenal paragangliomas are uncommon tumors arising from neuroectodermal-derived paraganglion tissue. These tumors are usually located in the carotid body, the jugulotympanic body or the mediastinum. A limited number of primary pulmonary paragangliomas have been reported previously. We present a case of a 63-year-old lady with a 12-pack-year smoking history and shortness of breath. Radiological investigations revealed a single right middle lobe pulmonary mass with homogenous density and lobulated borders on CT scan. The mass showed high fluorodeoxyglucose avidity on PET scan. A right middle lobectomy of the lung was performed. Macroscopic examination showed a well-defined yellow to cream mass measuring 28 mm in maximum dimension. Histologically, the mass was composed of alveolar pattern of spindle cells with granular cytoplasm. No lymph node metastasis was identified. Immunohistochemical stains performed showed that the tumour is positive for chromogranin, synaptophysin, TTF-1, but negative for CK7. S-100 stained the sustentacular cells in the tumour. While approximately 20% of carcinoid tumours are reported to be negative for keratins, the overall histological and radiological features are those of a paraganglioma. The case report describes the radiological and histopathological characteristics of this exceedingly rare tumour, thereby improving its understanding and helping in the differential diagnosis of pulmonary tumours.
dc.description.peerreviewedNo
dc.description.publicationstatusYes
dc.publisherLippincott Williams & Wilkins, Ltd.
dc.publisher.placeUnited Kingdom
dc.publisher.urihttps://www.iapcentral.org/meetings/iap-past-meetings-2019-2010/2014-bangkok
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofconferencenameCongress of the International Academy of Pathology 2014
dc.relation.ispartofconferencetitlePathology
dc.relation.ispartofdatefrom2014-10-05
dc.relation.ispartofdateto2014-10-10
dc.relation.ispartoflocationThailand, Bangkok
dc.rights.retentionY
dc.subject.fieldofresearchMedical and Health Sciences not elsewhere classified
dc.subject.fieldofresearchClinical Sciences
dc.subject.fieldofresearchcode119999
dc.subject.fieldofresearchcode1103
dc.titlePulmonary Paraganglioma: A case report.
dc.typeConference output
dc.type.descriptionE3 - Conferences (Extract Paper)
dc.type.codee3
gro.facultyGriffith Health Faculty
gro.hasfulltextNo Full Text
gro.griffith.authorLam, Alfred K.
gro.griffith.authorKasem, Kais Y.


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

  • Conference outputs
    Contains papers delivered by Griffith authors at national and international conferences.

Show simple item record