dc.contributor.author | Kasem, Kais Y. | |
dc.contributor.author | Lam, Alfred | |
dc.date.accessioned | 2015-02-27 | |
dc.date.accessioned | 2015-05-15T04:40:07Z | |
dc.date.accessioned | 2017-03-01T23:54:53Z | |
dc.date.available | 2015-05-15T04:40:07Z | |
dc.date.available | 2017-03-01T23:54:53Z | |
dc.date.issued | 2014 | |
dc.identifier.isbn | 0031-3025 | |
dc.identifier.uri | http://hdl.handle.net/10072/68010 | |
dc.description.abstract | Extra-adrenal paragangliomas are uncommon tumors arising from
neuroectodermal-derived paraganglion tissue. These tumors are
usually located in the carotid body, the jugulotympanic body or the
mediastinum. A limited number of primary pulmonary paragangliomas
have been reported previously. We present a case of a
63-year-old lady with a 12-pack-year smoking history and shortness
of breath. Radiological investigations revealed a single right
middle lobe pulmonary mass with homogenous density and lobulated
borders on CT scan. The mass showed high fluorodeoxyglucose
avidity on PET scan. A right middle lobectomy of the lung
was performed. Macroscopic examination showed a well-defined
yellow to cream mass measuring 28 mm in maximum dimension.
Histologically, the mass was composed of alveolar pattern of
spindle cells with granular cytoplasm. No lymph node metastasis
was identified. Immunohistochemical stains performed showed
that the tumour is positive for chromogranin, synaptophysin,
TTF-1, but negative for CK7. S-100 stained the sustentacular
cells in the tumour. While approximately 20% of carcinoid
tumours are reported to be negative for keratins, the overall
histological and radiological features are those of a paraganglioma.
The case report describes the radiological and histopathological
characteristics of this exceedingly rare tumour, thereby
improving its understanding and helping in the differential diagnosis
of pulmonary tumours. | |
dc.description.peerreviewed | No | |
dc.description.publicationstatus | Yes | |
dc.publisher | Lippincott Williams & Wilkins, Ltd. | |
dc.publisher.place | United Kingdom | |
dc.publisher.uri | https://www.iapcentral.org/meetings/iap-past-meetings-2019-2010/2014-bangkok | |
dc.relation.ispartofstudentpublication | N | |
dc.relation.ispartofconferencename | Congress of the International Academy of Pathology 2014 | |
dc.relation.ispartofconferencetitle | Pathology | |
dc.relation.ispartofdatefrom | 2014-10-05 | |
dc.relation.ispartofdateto | 2014-10-10 | |
dc.relation.ispartoflocation | Thailand, Bangkok | |
dc.rights.retention | Y | |
dc.subject.fieldofresearch | Medical and Health Sciences not elsewhere classified | |
dc.subject.fieldofresearch | Clinical Sciences | |
dc.subject.fieldofresearchcode | 119999 | |
dc.subject.fieldofresearchcode | 1103 | |
dc.title | Pulmonary Paraganglioma: A case report. | |
dc.type | Conference output | |
dc.type.description | E3 - Conferences (Extract Paper) | |
dc.type.code | e3 | |
gro.faculty | Griffith Health Faculty | |
gro.hasfulltext | No Full Text | |
gro.griffith.author | Lam, Alfred K. | |
gro.griffith.author | Kasem, Kais Y. | |