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  • Isolation and Structure of Some Constituents of the Australian Medicinal Plant, Tinospora smilacina (“Snakevine”).

    Author(s)
    Hungerford, Natasha Lynn
    Sands, Donald P. A.
    Kitching, William
    Griffith University Author(s)
    Hungerford, Natasha L.
    Year published
    1998
    Metadata
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    Abstract
    The structures of a number of compounds isolated from the stems of Tinospora smilacina (known as ‘snakevine’) have been determined. The known clerodane-type compound columbin is a major component, and two new minor compounds incorporate a heavily oxygenated tetrahydrofuran ring in place of the furan ring of columbin. The lignan isolariciresinol is also shown to be a minor component, along with dihydrosyringenin. The traditional medicinal use of the vine, particularly in countering snake venom, may be associated primarily with the presence of columbin.The structures of a number of compounds isolated from the stems of Tinospora smilacina (known as ‘snakevine’) have been determined. The known clerodane-type compound columbin is a major component, and two new minor compounds incorporate a heavily oxygenated tetrahydrofuran ring in place of the furan ring of columbin. The lignan isolariciresinol is also shown to be a minor component, along with dihydrosyringenin. The traditional medicinal use of the vine, particularly in countering snake venom, may be associated primarily with the presence of columbin.
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    Journal Title
    Australian Journal of Chemistry
    Volume
    51
    DOI
    https://doi.org/10.1071/C98034
    Subject
    Natural Products Chemistry
    Chemical Sciences
    Publication URI
    http://hdl.handle.net/10072/68107
    Collection
    • Journal articles

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