A continuous-flow droplet-based concentrator using ion concentration polarization
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We propose a method to continuously generate droplets with programmable concentration using the ion concentration polarization (ICP) phenomenon. The concentration of a sample in continuously formed droplets can be tuned with a combination of flow rate and applied voltage. The nanoporous junction needed for ICP was fabricated by embedding a Nafion membrane inside a PDMS mixture and then self-sealed by curing it. Compared to other methods previously reported in the literature, our fabrication method has the advantages of simplicity, reliability, repeatability and low-cost. Sample droplets with up to 100-fold concentration were generated continuously with our device.
Copyright 2015 Royal Society of Chemistry. This is the author-manuscript version of this paper. Reproduced in accordance with the copyright policy of the publisher. Please refer to the journal website for access to the definitive, published version.
Microelectromechanical Systems (MEMS)