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dc.contributor.authorHardcastle, Sharni
dc.contributor.authorBrenu, Ekua
dc.contributor.authorStaines, Don
dc.contributor.authorMarshall-Gradisnik, Sonya
dc.date.accessioned2017-05-03T16:11:04Z
dc.date.available2017-05-03T16:11:04Z
dc.date.issued2014
dc.identifier.issn23674792
dc.identifier.doi10.12988/bmgt.2014.3122
dc.identifier.urihttp://hdl.handle.net/10072/69289
dc.description.abstractChronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) is a multifactorial disorder defined by symptom-specific criteria and characterised by severe and prolonged fatigue. CFS/ME typically affects a variety of bodily systems, including the immune system. Patients with CFS/ME exhibit significantly reduced Natural Killer (NK) cell activity suggesting immune which may be hallmarks of changes in the adaptive immune system, potentially including T cell subsets and function. The principal purpose of T cells is to regulate immune responses and maintain immune homeostasis. These regulatory measures can often be compromised during illness and may present in a number of diseases including CFS/ME. This review paper examines the role of T cells in CFS/ME and the potential impact of T cells on CFS/ME immune profiles with an evaluation of the current literature.
dc.description.publicationstatusYes
dc.format.extent1023869 bytes
dc.format.mimetypeapplication/pdf
dc.languageEnglish
dc.language.isoeng
dc.publisherHikari
dc.publisher.placeBulgaria
dc.relation.ispartofstudentpublicationY
dc.relation.ispartofpagefrom25
dc.relation.ispartofpageto38
dc.relation.ispartofissue1
dc.relation.ispartofjournalBiological Markers and Guided Therapy
dc.relation.ispartofvolume1
dc.rights.retentionY
dc.subject.fieldofresearchCellular Immunology
dc.subject.fieldofresearchcode110704
dc.titleChronic Fatigue Syndrome/Myalgic Encephalomyelitis and the Potential Role of T Cells
dc.typeJournal article
dc.type.descriptionC2 - Articles (Other)
dc.type.codeC - Journal Articles
gro.rights.copyright© 2014 S. L. Hardcastle et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
gro.hasfulltextFull Text
gro.griffith.authorStaines, Don R.
gro.griffith.authorHardcastle, Sharni L.
gro.griffith.authorMarshall-Gradisnik, Sonya M.
gro.griffith.authorBrenu, Ekua


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