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  • Synthesis of N-alkylsulfonamides by borane-dimethyl sulfide reduction of N-acylsulfonamides

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    Author(s)
    James, Samantha N
    Coster, Mark J
    Griffith University Author(s)
    James, Samantha N.
    Coster, Mark J.
    Year published
    2015
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    Abstract
    A convenient synthesis of N-alkylsulfonamides in good to excellent yields by reduction of N-acylsulfonamides using BH3瓍e2 is described. This methodology presents an attractive alternative for sulfonamide formation.A convenient synthesis of N-alkylsulfonamides in good to excellent yields by reduction of N-acylsulfonamides using BH3瓍e2 is described. This methodology presents an attractive alternative for sulfonamide formation.
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    Journal Title
    Tetrahedron Letters
    Volume
    56
    DOI
    https://doi.org/10.1016/j.tetlet.2015.03.008
    Copyright Statement
    © 2015, Elsevier. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (http://creativecommons.org/licenses/by-nc-nd/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, providing that the work is properly cited.
    Subject
    Medicinal and biomolecular chemistry
    Organic chemistry
    Organic chemical synthesis
    Publication URI
    http://hdl.handle.net/10072/69426
    Collection
    • Journal articles

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