Synthesis of N-alkylsulfonamides by borane-dimethyl sulfide reduction of N-acylsulfonamides
Abstract
A convenient synthesis of N-alkylsulfonamides in good to excellent yields by reduction of N-acylsulfonamides using BH3瓍e2 is described. This methodology presents an attractive alternative for sulfonamide formation.
Journal Title
Tetrahedron Letters
Volume
56
Copyright Statement
© 2015, Elsevier. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (http://creativecommons.org/licenses/by-nc-nd/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, providing that the work is properly cited.
Subject
Organic Chemical Synthesis
Medicinal and Biomolecular Chemistry
Organic Chemistry