Now showing items 23796-23815 of 39864

    • N(1),N(1)-Dimethyl-N(3)-(3-(trifluoromethyl)phenethyl)propane-1,3-diamine, a new lead for the treatment of human African trypanosomiasis 

      Pham, Ngoc; Deydier, Sophie; Labaied, Mehdi; Monnerat, Séverine; Stuart, Kenneth; Quinn, Ronald (European Journal of Medicinal Chemistry, 2014)
      The natural product, convolutamine I (1), has anti-trypanosomal activity however it has a high molecular weight of 473 due to a presence of 3 bromine atoms. The synthesis of the natural product convolutamine I (1) together ...
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    • N- and O-glycomics from minor amounts of formalin-fixed, paraffin-embedded tissue samples 

      Hinneburg, Hannes; Schirmeister, Falko; Korac, Petra; Kolarich, Daniel (Methods in Molecular Biology, 2017)
      The availability of well-defined samples in sufficient numbers represents a major bottleneck for any biomarker related research. The utilization of preserved, archived and clinically well-described samples therefore holds ...
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    • N-(2-Nitrobenzenesulfonyl)-L-alanine methyl ester 

      Bornaghi, Laurent; Poulsen, Sally-Ann; Healy, Peter; White, Alan (Acta crystallographica. Section E, Structure reports online, 2005)
      The structure of the title compound, C10H12N2O6S, has been determined as part of an ongoing investigation into the preparation of substituted amino acids suitable for the generation of combinatorial libraries. The molecular ...
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    • N-(2-Nitrophenylsulfonyl)glycine methyl ester 

      Bornaghi, Laurent; Poulsen, Sally-Ann; Healy, Peter; White, Alan (Acta crystallographica. Section E, Structure reports online, 2005)
      The structure of the title compound, C9H10N2O6S, has been determined as part of an ongoing investigation into the preparation of N-allyl-substituted amino acids suitable for alkene cross-metathesis reactions in the generation ...
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    • N-(4,6-Dimethylpyrimidin-2-yl)-4-(oxolan-2-ylamino)benzenesulfonamide 

      D. Arman, Hadi; Kaulgud, Trupta; R. T. Tiekink, Edward; Young, David (Acta Crystallographica. Section E: Structure Reports Online, 2009)
      The title compound, C16H20N4O 3S, adopts an l-shaped conformation, as seen by the dihedral angle of 76.93 (7)ࠦormed between the two aromatic rings. The most notable feature of the crystal packing is the formation of N- H?O ...
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    • N-allyl-N-(2-nitrobenzenesulfonyl)-L-leucine methyl ester 

      Bornaghi, Laurent; Poulsen, Sally-Ann; Healy, Peter (ACTA Crystallographica Section E - Structure Reports Online, 2004)
      The structure of the title compound, C16H22N2O6S, has been determined as part of an ongoing investigation into the preparation of N-alkylated amino acid precursors for alkene cross-metathesis reactions for the generation ...
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    • N-Allyl-N-(2-nitrobenzenesulfonyl)-L-phenylalanine methyl ester 

      Poulsen, Sally-Ann; Noack, Cassandra; Healy, Peter (ACTA Crystallographica Section E - Structure Reports Online, 2003)
      The structure of the title compound, C19H20N2O6S, has been determined as part of an ongoing investigation into the preparation of bis-N-alkyl�ed amino acids for subsequent alkene cross-metathesis reactions to generate ...
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    • N-Aryl-2-aminobenzimidazoles: Novel, Efficacious, Antimalarial Lead Compounds 

      Ramachandran, Sreekanth; Hameed P., Shahul; Srivastava, Abhishek; Shanbhag, Gajanan; Morayya, Sapna; Rautela, Nikhil; Awasthy, Disha; Kavanagh, Stefan; Bharath, Sowmya; Reddy, Jitendar; Panduga, Vijender; Prabhakar, K.; Saralaya, Ramanatha; Nanduri, Robert; Raichurkar, Anandkumar; Menasinakai, Sreenivasaiah; Achar, Vijayashree; Jiménez-Díaz, María Belén; Martínez, María Santos; Angulo-Barturen, In̿igo; Ferrer, Santiago; Sanz, Laura María; Gamo, Francisco Javier; Duffy, Sandra; Avery, Vicky; Waterson, David; C. S. Lee, Marcus; Coburn-Flynn, Olivia; A. Fidock, David; al, et (Journal of Medicinal Chemistry, 2014)
      From the phenotypic screening of the AstraZeneca corporate compound collection, N-aryl-2-aminobenzimidazoles have emerged as novel hits against the asexual blood stage of Plasmodium falciparum (Pf). Medicinal chemistry ...
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    • N-benzyl-2-(3-chloro-4-hydroxyphenyl)acetamide 

      Davis, Rohan; Healy, Peter (Acta crystallographica. Section E, Structure reports online, 2010)
      The title compound, C15H14ClNO2, was synthesized as part of a project to generate a combinatorial library based on the fungal natural product 2-(3-chloro-4-hydroxyphenyl)acetamide. It crystallizes as non-planar discrete ...
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    • N-cinnamoyl-L-phenylalanine methyl ester 

      Bornaghi, Laurent; Poulsen, Sally-Ann; Healy, Peter; White, Alan (Acta Crystallographica. Section E: Structure reports online, 2008)
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    • N-Cinnamoyl-L-valine methyl ester 

      Bornaghi, Laurent; Poulsen, Sally-Ann; Healy, Peter; White, Alan (Acta Crystallographica. Section E: Structure reports online, 2007)
      The crystal structure of the title compound, C15H19NO3, shows that the overall molecular conformation, which is approximately planar, is stabilized by intermolecular N-H...O hydrogen-bonding interactions.
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    • N-glycan MALDI imaging mass spectrometry on formalin-fixed paraffin-embedded tissue enables the delineation of ovarian cancer tissues 

      Everest-Dass, Arun V.; Briggs, Matthew T.; Kaur, Gurjeet; Oehler, Martin K.; Hoffmann, Peter; Packer, Nicolle H. (Molecular and Cellular Proteomics, 2016)
      Ovarian cancer is a fatal gynaecological malignancy in adult women with a five-year overall survival rate of only 30%. Glycomic and glycoproteomic profiling studies have reported extensive protein glycosylation pattern ...
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    • N-Glycan matrix-assisted laser desorption/ionization mass spectrometry imaging protocol for formalin-fixed paraffin-embedded tissues 

      Briggs, Matthew T.; Ho, Yin Ying; Kaur, Gurjeet; Oehler, Martin K.; Everest-Dass, Arun V.; Packer, Nicolle H.; Hoffmann, Peter (Rapid Communications in Mass Spectrometry, 2017)
      Rationale: Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) of the proteome of a tissue has been an established technique for the past decade. In the last few years, MALDI-MSI of the ...
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    • N-glycans modulate the function of human corticosteroid-binding globulin 

      Sumer-Bayraktar, Zeynep; Kolarich, Daniel; Campbell, Matthew P.; Ali, Sinan; Packer, Nicolle H.; Thaysen-Andersen, Morten (Molecular and Cellular Proteomics, 2011)
      Human corticosteroid-binding globulin (CBG), a heavily glycosylated protein containing six N-linked glycosylation sites, transports cortisol and other corticosteroids in blood circulation. Here, we investigate the biological ...
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    • N-heterocyclic carbene Pt(II) complexes from caffeine: synthesis, structures and photoluminescent properties 

      Hu, Jian Jin; Bai, Shi-Qiang; Yeh, Hsiu Hsuan; J. Young, David; Chi, Yun; Andy Hor, T. (Dalton Transactions, 2011)
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    • N-nitrosodimethylamine and trihalomethane formation and minimisation in Southeast Queensland drinking water 

      Knight, Nicole; Watson, Kalinda; Farré, Maria José; Shaw, Glendon (Environmental Monitoring and Assessment, 2012)
      This study assesses the prevalence of disinfection by-product (DBP) precursors in some Southeast Queensland drinking water sources by conducting formation potential experiments for the four regulated trihalomethanes (THMs), ...
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    • N-of-1 randomized trials to assess the efficacy of gabapentin for chronic neuropathic pain 

      Yelland, Michael; J. Poulos, Christopher; I. Pillans, Peter; M. Bashford, Guy; Nikles, Catherine Jane; M. Sturtevant, Joanna; Vine, Norma; B. Del Mar, Christopher; J. Schluter, Philip; Tan, Meng; Chan, Jonathan; Mackenzie, Fraser; Brown, Robyn (Pain Medicine, 2009)
      Objective. The objective of this study was to compare the efficacy of gabapentin with placebo for neuropathic pain at the individual and population levels. Design. This study used an n-of-1 trial methodology with three ...
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    • N-type Cu2O film for photocatalytic and photoelectrocatalytic processes: Its stability and inactivation of E. coli 

      Xiong, Liangbin; Ng, Tsz Wai; Yu, Ying; Xia, Dehua; Yip, Ho Yin; Li, Guiying; An, Taicheng; Zhao, Huijun; Wong, Po Keung (Electrochimica Acta, 2015)
      Photoelectrocatalytic (PEC) inactivation of Escherichia coli K-12 by cuprous oxide (Cu2O) film irradiated by visible light is firstly reported. A complete inactivation of about 7 log of E. coli was obtained for Cu2O film ...
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    • N-{2-[4-(Aminosulfonyl)phenyl]ethyl}-2-(4-hydroxy-phenyl)acetamide 

      Davis, Rohan; Healy, Peter; Poulsen, Sally-Ann (Acta Crystallographica. Section E: Structure reports online, 2007)
      The crystal structure of the title sulfonamide, C16H18N2O4S, is stabilized by strong N-H...O and O-H...O intermolecular hydrogen bonds.
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    • N.M.R. studies of some chromium(III) dithiocarbamate complexes 

      Golding, R.; Healy, P.; Colombera, P.; White, A. (Australian Journal of Chemistry, 1974)
      The temperature dependence of the proton N.M.R. spectra of some simple tris(N,N-disubstituted dithiocarbamato)chromium(111) derivatives, [Cr(S2CNR2)3], has been studied in deuterochloroform solution over the range ? 60꠴o ...
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