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dc.contributor.authorAzimi, Paria
dc.contributor.authorGhiasvand, Reza
dc.contributor.authorFeizi, Awat
dc.contributor.authorHosseinzadeh, Javad
dc.contributor.authorBahreynian, Maryam
dc.contributor.authorHariri, Mitra
dc.contributor.authorKhosravi-Boroujeni, Hossein
dc.date.accessioned2017-06-19T01:51:39Z
dc.date.available2017-06-19T01:51:39Z
dc.date.issued2016
dc.identifier.issn0803-7051
dc.identifier.doi10.3109/08037051.2015.1111020
dc.identifier.urihttp://hdl.handle.net/10072/99457
dc.description.abstractHerbal medicines with high amounts of phytochemicals have been shown to have beneficial effects on blood pressure (BP), endothelial function and anthropometric measures. This study aimed to determine the effect of herbal treatment on BP, endothelial function and anthropometric measures in patients with type 2 diabetes mellitus (T2DM). This clinical trial included 204 T2DM patients randomly assigned to four intervention groups receiving 3 g cinnamon, 3 g cardamom, 1 g saffron or 3 g ginger with three glasses of black tea, and one control group consuming only three glasses of tea without any herbals, for 8 weeks. Intercellular adhesion molecule-1 (ICAM-1), systolic and diastolic BP and anthropometric measures were collected at baseline and after 8 weeks. No significant difference was found between various medicinal plants in terms of influencing BP, serum soluble (s)ICAM-1 concentrations and anthropometric measures. However, in within-group comparison saffron and ginger intakes significantly reduced sICAM-1 concentrations (340.9 ± 14.4 vs 339.69 ± 14.4 ng/ml, p = 0.01, and 391.78 ± 16.0 vs 390.97 ± 15.8 ng/ml, p = 0.009, respectively) and ginger intake affected systolic BP (143.06 ± 0.2 vs 142.07 ± 0.2 mmHg, p = 0.02). Although administration of these herbal medicines as supplementary remedies could affect BP and sICAM-1 concentrations, there was no significant difference between the plants in terms of influencing anthropometric measures, BP and endothelial function.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherTaylor & Francis
dc.relation.ispartofpagefrom133
dc.relation.ispartofpageto140
dc.relation.ispartofissue3
dc.relation.ispartofjournalBlood Pressure
dc.relation.ispartofvolume25
dc.subject.fieldofresearchClinical sciences
dc.subject.fieldofresearchClinical sciences not elsewhere classified
dc.subject.fieldofresearchcode3202
dc.subject.fieldofresearchcode320299
dc.titleEffect of cinnamon, cardamom, saffron and ginger consumption on blood pressure and a marker of endothelial function in patients with type 2 diabetes mellitus: A randomized controlled clinical trial
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
dc.description.versionAccepted Manuscript (AM)
gro.rights.copyright© 2016 Taylor & Francis. This is an Accepted Manuscript of an article published by Taylor & Francis in Blood Pressure on 12 Jan 2016, available online: http://www.tandfonline.com/doi/full/10.3109/08037051.2015.1111020
gro.hasfulltextFull Text
gro.griffith.authorKhosravi Boroujeni, Hossein


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