Family-centred care (FCC) is an approach to healthcare that occurs within varied paediatric care settings with the belief that this model of care meets the psychosocial, emotional, and physical needs of the hospitalised child and family. This review aimed to explore the attitudes, perceptions, knowledge and implementation of FCC from many studies and to facilitate a wider and more thorough understanding of this practice from a diverse sample of nurses working in paediatric care settings. Method The review was completed using the Joanna Briggs Institute (JBI) Systematic Review Method. Seven databases (MEDLINE, EMBASE, CINAHL, JBI, ProQuest, PsycINFO, and Cochrane Library) were searched for research associated with FCC in paediatric care settings published between January 2013 and May 2024. Aim To identify, appraise, and synthesise extant literature on the prevalence and practices to enhance family-centred care among nurses working in paediatric care settings, as this can help to evaluate their existing state of awareness, experience, and training. Results Of the 644 potentially relevant studies identified, and following title and abstract screening according to the inclusion criteria, 55 papers were selected for retrieval. Of these, 16 met the inclusion criteria. Quality assessment was completed using the MMAT appraisal tool. Conclusion FCC in pediatric care settings is significant as it can benefit children to be supported by their families when they are admitted to a care setting. Nevertheless, nurses require the right attitudes, perception and knowledge regarding FCC concepts and principles, which can enhance the efficacy of practicing FCC.