Few-Layer Graphdiyne Nanosheets Applied for Multiplexed Real-Time DNA Detection

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Parvin, Nargish
Jin, Quan
Wei, Yanze
Yu, Ranbo
Zheng, Bing
Huang, Ling
Zhang, Ying
Wang, Lianhui
Zhang, Hua
Gao, Mingyuan
Zhao, Huijun
Hu, Wenping
Li, Yuliang
Wang, Dan
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2017
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Abstract

Despite recent progress in 2D nanomaterials-based biosensing, it remains challenging to achieve sensitive and high selective detection. This study develops few-layer graphdiyne (GD) nanosheets (NSs) that are used as novel sensing platforms for a variety of fluorophores real-time detection of DNA with low background and high signal-to-noise ratio, which show a distinguished fluorescence quenching ability and different affinities toward single-stranded DNA and double-stranded DNA. Importantly, for the first time, a few-layer GD NSs-based multiplexed DNA sensor is developed.

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Advanced Materials

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29

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18

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Physical sciences

Chemical sciences

Engineering

Materials engineering not elsewhere classified

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