Few-Layer Graphdiyne Nanosheets Applied for Multiplexed Real-Time DNA Detection
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Jin, Quan
Wei, Yanze
Yu, Ranbo
Zheng, Bing
Huang, Ling
Zhang, Ying
Wang, Lianhui
Zhang, Hua
Gao, Mingyuan
Zhao, Huijun
Hu, Wenping
Li, Yuliang
Wang, Dan
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Abstract
Despite recent progress in 2D nanomaterials-based biosensing, it remains challenging to achieve sensitive and high selective detection. This study develops few-layer graphdiyne (GD) nanosheets (NSs) that are used as novel sensing platforms for a variety of fluorophores real-time detection of DNA with low background and high signal-to-noise ratio, which show a distinguished fluorescence quenching ability and different affinities toward single-stranded DNA and double-stranded DNA. Importantly, for the first time, a few-layer GD NSs-based multiplexed DNA sensor is developed.
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Advanced Materials
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29
Issue
18
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Physical sciences
Chemical sciences
Engineering
Materials engineering not elsewhere classified