In the last decade, virtual reality technology has become widely available to the public and is now used for a variety of applications in industries such as education, medicine and entertainment. One of the most important problems however, is virtual reality sickness which most users will experience. It is similar to similar to motion sickness, and thought to be caused by a mismatch of sensory signals that occur when the virtual experience does not match the real world. This thesis presents a mixed methods research project, that was undertaken using the Design Science methodology. A literature review was completed that defined what virtual reality sickness is, factors that are known to influence it and ways that these factors are being addressed in modern virtual reality technology. A comparison of migraine triggers against these factors was conducted, which showed many similarities between the two conditions, and provided a list of potential sickness factors for the research project to investigate. A series of experiments were run to investigate these factors, using a HTC Vive as the virtual reality headset, and a custom built Unity application to provide participants with tasks to complete. It required navigating a large virtual environment, interacting with a cockpit control system and completing a list of tasks within that space.