Maternal Mortality Rate (MMR) in Indonesia is relatively high when compared with ASEAN member countries. In 2012, MMR in Indonesia amounts to 359/100,000 live births. The main cause of maternal mortality in Indonesia is bleeding factor. The prevalence of iron deficiencyanemia among 15-24 year old girls in Indonesia is 18.4%. This study was conducted to determine the factors affecting the intention of adolescent girls in consuming Fe tablets as an effort to prevent anemia in Vocational High School (SMK) Wachid Hasyim 1 Surabaya. This research uses analytic observational method with cross sectional research design. Sampling technique using purposive sampling with the number of samples obtained as many as 63 students. The independent variables were perceived benefit and perceived self efficacy. The results showed that there was a significant influence perceived self efficacy (p-value= 0,041) and whereas perceived benefit did not have intention of adolescent girls in consuming Fe tablet. Factors that affect the intention of adolescent girls in consuming Fe tablets is perceived self efficacy.