Introduction: Peripherally inserted central catheter (PICC) has been recognised as an effective and safe vascular access device. There is a range of devices and management methods in regard to PICC, yet there is little synthesis of the evidence around non-patient related factors of PICC infections to provide an evidence-based guide for clinicians. This integrative review aimed to identify the non-patient related factors that influence PICC infections in adult patients.

Method: An integrative review was conducted across online databases.

Results: Twenty-five articles were analysed to identify non-patient related factors that influence CRBSI rates. The catheter type, insertion technique and maintenance were key factors in the infection rates in PICC.

Conclusion: This integrative review highlighted the importance of considering non-patient related factors to achieve the lowest PICC infection. There is a need for high-level studies to investigate non-patient related factors in preventing PICC infection to increase the evidence base.