Papaya (Carica papaya L.) is one of the major tropical fruit crops worldwide; however, commercial and local production is reduced by several diseases and pests. Papaya Ringspot Virus type P (PRSV-P) is a serious disease of Carica papaya, and all known varieties of papaya are susceptible. Vasconcellea parviflora is a PRSV-P susceptible species. Researchers have identified PRSV-P resistant genes in Vasconcellea spp., which were formerly included in the genus Carica. Of the 21 Vasconcellea species, only one, Vasconcellea pubescens sometimes called Vasconcellea cundinamarcensis, has been consistently reported worldwide to be resistant or immune to PRSV-P for more than 60 years.