Synthesis of N1,N3-disubstituted formamidrazones via the TMSCl-promoted reaction of isocyanides with thiosemicarbazones

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Sarnpitak, Pakornwit
Tsirulnikov, Sergey
Krasavin, Mikhail
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2012
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Abstract

A hitherto undescribed TMSCl-promoted reaction of thiosemicarbazones was found to give rare N1,N3-disubstituted formamidrazones in fair to excellent yields. The scope of this new reaction was investigated and a plausible mechanism proposed.

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Tetrahedron Letters

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53

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48

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© 2012 Elsevier. This is the author-manuscript version of this paper. Reproduced in accordance with the copyright policy of the publisher. Please refer to the journal's website for access to the definitive, published version.

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Medicinal and Biomolecular Chemistry not elsewhere classified

Medicinal and Biomolecular Chemistry

Organic Chemistry

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