Chirality of glutathione surface coating affects the cytotoxicity of quantum dots

No Thumbnail Available
File version
Author(s)
Li, Yiye
Zhou, Yunlong
Wang, Hai-Yan
Perrett, Sarah
Zhao, Yuliang
Tang, Zhiyong
Nie, Guangjun
Griffith University Author(s)
Primary Supervisor
Other Supervisors
Editor(s)
Date
2011
Size
File type(s)
Location
License
Abstract

Choose your poison: Chiral CdTe quantum dots (QDs) coated with L- or D-glutathione (GSH) stabilizers exhibit differences in cytotoxicity although they have identical composition and size. D-GSH-QDs are less cytotoxic than L-GSH-QDs. The ability of QDs to induce cell death is correlated with their ability to induce autophagy, which is chirality-dependent (see picture).

Journal Title

Angewandte Chemie (International Edition)

Conference Title
Book Title
Edition
Volume

50

Issue

26

Thesis Type
Degree Program
School
Publisher link
Patent number
Funder(s)
Grant identifier(s)
Rights Statement
Rights Statement
Item Access Status
Note
Access the data
Related item(s)
Subject

Chemical sciences

Macromolecular and materials chemistry not elsewhere classified

Persistent link to this record
Citation
Collections