Multiple sclerosis: Diagnosis, disease-modifying therapy and prognosis

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Travers, Brett S
Tsang, Benjamin K-T
Barton, Joshua L
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2022
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Background: Multiple sclerosis (MS) is a multifocal inflammatory central nervous system disorder. There are now many highly effective disease-modifying therapies (DMTs) available as treatment options, which have a significant impact on disease activity and long-term disability. Objective: The aim of this article is to provide a concise overview of the diagnosis, DMTs and prognosis of MS. Discussion: The diagnosis of MS is made on clinicoradiological grounds to prove dissemination of disease in both time and space in the nervous system. While the expanding options of DMTs have had a significant impact on disability, they make medication selection for individual patients more complicated. Patients with MS often have a model of care shared between the neurologist and the general practitioner. This review article summarises the key aspects of the diagnosis, DMTs and prognosis of MS relevant to the general practitioner.

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Australian Journal of General Practice
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51
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4
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Travers BS, Tsang BKT, and Barton JL. Multiple sclerosis: Diagnosis, disease-modifying therapy and prognosis. Australian Journal of General Practice 2022:51(4):199-206. Available at http://doi.org/10.31128/AJGP-07-21-6103
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Immunology
Biomedical and clinical sciences
Science & Technology
Life Sciences & Biomedicine
Medicine, General & Internal
General & Internal Medicine
PLACEBO-CONTROLLED TRIAL
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Travers, BS; Tsang, BK-T; Barton, JL, Multiple sclerosis: Diagnosis, disease-modifying therapy and prognosis, Australian Journal of General Practice, 2022, 51 (4), pp. 199-206
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