Myocardial infarction from isolated coronary artery vasculitis in a young patient: A rare case

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Markham, Ryan
Rahman, Atifur
Tai, Shayan
Hamilton-Craig, Ian
Hamilton-Craig, Christian
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2015
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Abstract

Symptomatic coronary artery disease (CAD) primarily occurs in patients over the age of 40, however younger men and women can also be affected. The pathophysiology of CAD in this group is often not due to atherosclerotic plaque rupture, except for those with genetically predetermined risk such as familial hypercholesterolaemia. In an autopsy study of victims aged 15–34 years, advanced coronary atheromas were seen only in 2% of males aged 15–19 years, and none in females [ 1 ]. Many of these cases may have had severe heterozygous familial hypercholesterolaemia (FH), which occurs with a frequency of 1:300–1:500 of the general population, and in which total cholesterol levels are very high (usually > 8 mmol/L) [ 2 ].

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International Journal of Cardiology

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180

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Cardiovascular medicine and haematology

Science & Technology

Life Sciences & Biomedicine

Cardiac & Cardiovascular Systems

Cardiovascular System & Cardiology

Acute coronary syndrome

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Markham, R; Rahman, A; Tai, S; Hamilton-Craig, I; Hamilton-Craig, C, Myocardial infarction from isolated coronary artery vasculitis in a young patient: A rare case, International Journal of Cardiology, 2015, 180, pp. 40-41

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