Untreated, severe hypotension rapidly results in end-organ hypoperfusion and death.1 Vasopressors are effective at increasing blood pressure; therefore, the infusion of vasopressors to avoid hypotension is a key intensive care unit (ICU) therapy.2 Current guidelines suggest targeting a mean arterial pressure (MAP) of 65 mmHg in adults with septic shock.3 Despite this MAP levels in ICU, patients receiving vasopressors often exceed this and recent evidence suggests that, compared to usual practice, targeting a lower MAP, effectively minimising exposure to vasopressors, may reduce mortality in patients with vasodilatory shock.4,5