Antibody and T cell responses against avian and microbial antigens associate with hypersensitivity pneumonitis disease parameters in pigeon breeders
File version
Author(s)
Jozwik, Agnieszka
Heaps, Adrian
Kakkar, Nirupma
Donnelly, Iona
Cookson, Sharon
Bourke, Stephen J
McSharry, Charles
Todryk, Stephen M
Griffith University Author(s)
Primary Supervisor
Other Supervisors
Editor(s)
Date
Size
File type(s)
Location
License
Abstract
Pigeon Fancier's Lung (PFL) is a form of Hypersensitivity Pneumonitis where lung pathology occurs due to an immune reaction to repeated inhalation of large amounts of feather-derived and droppings-derived dust [1]. The 1μm dust particles penetrate the lower respiratory tract, initiating characteristic granulomatous inflammation in distal airways and alveoli. The particles, which carry pigeon antigens, cause irritation, and likely contain microbial components, both of which enhance immunogenicity.
Journal Title
Allergy
Conference Title
Book Title
Edition
Volume
Issue
Thesis Type
Degree Program
School
Publisher link
Patent number
Funder(s)
Grant identifier(s)
Rights Statement
Rights Statement
Item Access Status
Note
This publication has been entered into Griffith Research Online as an Advanced Online Version.
Access the data
Related item(s)
Subject
Immunology
T cells
antibodies
biomarkers
hypersensitivity pneumonitis
lung function
Persistent link to this record
Citation
Hasan, SF; Jozwik, A; Heaps, A; Kakkar, N; Donnelly, I; Cookson, S; Bourke, SJ; McSharry, C; Todryk, SM, Antibody and T cell responses against avian and microbial antigens associate with hypersensitivity pneumonitis disease parameters in pigeon breeders., Allergy, 2019