STUDY OBJECTIVE: To validate the PIPPA (Period ImPact and Pain Assessment) self-screening tool for menstrual disturbance in teenagers. DESIGN: Cross-sectional study. SETTING: Three Senior High Schools in the Australian Capital Territory (ACT), Australia. PARTICIPANTS: 1066 girls aged between 15 and 19 years INTERVENTIONS AND MAIN OUTCOME MEASURES: A quantitative paper survey collected self-reports of menstrual bleeding patterns, typical and atypical symptoms, morbidities and interference with daily activities. Multiple correspondence analysis (MCA) was used to examine associations between PIPPA questions. Generalised linear models compared total score and sub scores by validation criteria: pain, school absence and BMI. Receiver operating characteristic (ROC) curves were used to evaluate the predictiveness of menstrual disturbance indicators by total PIPPA score. RESULTS: Reports of pain, interference and concern within the PIPPA items and between both the MDOT and PIPPA questionnaires were significantly correlated (p< 0.0001). The indicator 'missing school' was highly associated (p<0.0001) with pain and interference. Obesity (BMI ≥30) was associated with higher PIPPA scores as was underweight (BMI≤18.4). Where 0=no disturbance, 5=high disturbance, aggregated PIPPA scores found 75% scoring 0-2 (out of 5), 25% scoring 3-5 (257/1037). High scores of 4 or 5 (out of 5) were 7% (72/1037) and 3.7% (38/1037) respectively. CONCLUSIONS: PIPPA is a valid screening tool for pain related menstrual disturbance that effects functioning in young women. PIPPA subdomains of pain/interference have good validity relative to indicators of pain and interference and are responsive to age, BMI and school absence differences.