Sideroxylonal C, a New Inhibitor of Human Plasminogen Activator Inhibitor Type-1, from the Flowers of Eucalyptus albens
No Thumbnail Available
File version
Author(s)
Neve, J
Leone, PD
Carroll, AR
Moni, RW
Paczkowski, NJ
Pierens, G
Bjorquist, P
Deinum, J
Ehnebom, J
Inghardt, T
Guymer, G
Grimshaw, P
Quinn, RJ
Leone, PD
Carroll, AR
Moni, RW
Paczkowski, NJ
Pierens, G
Bjorquist, P
Deinum, J
Ehnebom, J
Inghardt, T
Guymer, G
Grimshaw, P
Quinn, RJ
Griffith University Author(s)
Primary Supervisor
Other Supervisors
Editor(s)
Date
1999
Size
File type(s)
Location
License
Abstract
Sideroxylonal C (3), a new phloroglucinol dimer, was isolated from the flowers of Eucalyptus albens through bioassay-guided fractionation. The structure elucidation was based on 1D and 2D NMR experiments, MS analysis, and comparison with sideroxylonals A (1) and B (2). Sideroxylonal C inhibited human plasminogen activator inhibitor type-1 at 4.7 μM without any significant effect on human tissue plasminogen activator.
Journal Title
Journal of Natural Products
Conference Title
Book Title
Edition
Volume
62
Issue
2
Thesis Type
Degree Program
School
Publisher link
Patent number
Funder(s)
Grant identifier(s)
Rights Statement
Rights Statement
Item Access Status
Note
Access the data
Related item(s)
Subject
Chemical sciences
Biological sciences
Biomedical and clinical sciences
History, heritage and archaeology
Traditional, complementary and integrative medicine