The Presentation of Depression in Depressed Autistic Individuals: A Systematic Review
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Paynter, Jessica
Dargue, Nicole
Adams, Dawn
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Abstract
This systematic literature review examines the varied presentations of depression in depressed autistic individuals, including symptoms beyond DSM-5-TR criteria. A search of five databases (updated February 2024) identified 24 studies, encompassing 243 autistic individuals. Study quality varied, assessed using QuADS. The review was pre-registered with PROSPERO (CRD42022355322). Results were synthesised based on DSM-5-TR criteria and additional presentations, including who reported them. Findings showed 91.66% of studies reported presentations beyond DSM-5-TR criteria. Additionally, some DSM-5-TR symptoms may present differently in autistic individuals. Variations in depressive signs were noted across self-reports, informant-reports, interviews, and questionnaires. Clarifying whether these additional presentations are autism-specific, arise from the intersection of autism and depression, or manifestations of a depressive disorder is necessary for refining diagnostic tools.
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Review Journal of Autism and Developmental Disorders
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© The Author(s) 2024. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
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Neurosciences
Applied and developmental psychology
Biological psychology
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Hinze, E; Paynter, J; Dargue, N; Adams, D, The Presentation of Depression in Depressed Autistic Individuals: A Systematic Review, Review Journal of Autism and Developmental Disorders, 2024