Low-Intensity Pulsed Ultrasound Stimulation for Bone Fractures Healing: A Review

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Palanisamy, Poornima
Alam, Monzurul
Li, Shuai
Chow, Simon KH
Zheng, Yong-Ping
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2022
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Abstract

Low-intensity pulsed ultrasound (LIPUS) is a developing technology, which has been proven to improve fracture healing process with minimal thermal effects. This noninvasive treatment accelerates bone formation through various molecular, biological, and biomechanical interactions with tissues and cells. Although LIPUS treatment has shown beneficial effects on different bone fracture locations, only very few studies have examined its effects on deeper bones. This study provides an overview on therapeutic ultrasound for fractured bones, possible mechanisms of action, clinical evidences, current limitations, and its future prospects.

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Journal of Ultrasound in Medicine

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41

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3

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© 2021 The Authors. Journal of Ultrasound in Medicine published by Wiley Periodicals LLC on behalf of American Institute of Ultrasound in Medicine. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial- NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Clinical sciences

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Life Sciences & Biomedicine

Acoustics

Radiology, Nuclear Medicine & Medical Imaging

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Palanisamy, P; Alam, M; Li, S; Chow, SKH; Zheng, Y-P,Low-Intensity Pulsed Ultrasound Stimulation for Bone Fractures Healing: A Review, Journal of Ultrasound in Medicine, 2022, 41 (3), pp. 547-563

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