Establishing the sensitivity and specificity of the gynaecological cancer distress screen
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Harbeck, E
Anderson, D
Porter-Steele, J
Nehill, C
Sanmugarajah, J
Perrin, L
Shannon, C
Cabraal, N
Jennings, B
Otton, G
Adams, C
Mellon, A
Chambers, S
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Abstract
Objective Nuanced distress screening tools can help cancer care services manage specific cancer groups' concerns more efficiently. This study examines the sensitivity and specificity of a tool specifically for women with gynaecological cancers (called the Gynaecological Cancer Distress Screen or DT-Gyn).
Methods This paper presents cross-sectional data from individuals recently treated for gynaecological cancer recruited through Australian cancer care services, partner organisations, and support/advocacy services. Receiver operating characteristics analyses were used to evaluate the diagnostic accuracy of the DT-Gyn against criterion measures for anxiety (GAD-7), depression (patient health questionnaire), and distress (IES-R and K10).
Results Overall, 373 individuals aged 19–91 provided complete data for the study. Using the recognised distress thermometer (DT) cut-off of 4, 47% of participants were classified as distressed, while a cut-off of 5 suggested that 40% had clinically relevant distress. The DT-Gyn showed good discriminant ability across all measures (IES-R: area under the curve (AUC) = 0.86, 95% CI = 0.82–0.90; GAD-7: AUC = 0.89, 95% CI = 0.85–0.93; K10: AUC = 0.88, 95% CI = 0.85–0.92; PHQ-9: AUC = 0.85, 95% CI = 0.81–0.89) and the Youden Index suggested an optimum DT cut-point of 5.
Conclusions This study established the psychometric properties of the DT-Gyn, a tool designed to identify and manage the common sources of distress in women with gynaecological cancers. We suggest a DT cut point ≥5 is optimal in detecting ‘clinically relevant’ distress, anxiety, and depression in this population.
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Psycho-Oncology
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33
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3
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Oncology and carcinogenesis
Obstetrics and gynaecology
Biomedical and clinical sciences
Psychology
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Seib, C; Harbeck, E; Anderson, D; Porter-Steele, J; Nehill, C; Sanmugarajah, J; Perrin, L; Shannon, C; Cabraal, N; Jennings, B; Otton, G; Adams, C; Mellon, A; Chambers, S, Establishing the sensitivity and specificity of the gynaecological cancer distress screen, Psycho-Oncology, 2024, 33 (3), pp. e6328-