Deep learning Enables Accurate Diagnosis of Novel Coronavirus (COVID-19) with CT images

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Song, Y
Zheng, S
Li, L
Zhang, X
Zhang, X
Huang, Z
Chen, J
Wang, R
Zhao, H
Zha, Y
Shen, J
Chong, Y
Yang, Y
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2021
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Abstract

A novel coronavirus (COVID-19) has emerged recently as an acute respiratory syndrome. The outbreak was originally reported in Wuhan, China, but has subsequently been spread world-widely. As the COVID-19 continues to spread rapidly across the world, computed tomography (CT) has become essentially important for fast diagnoses. Thus, it is urgent to develop an accurate computer-aided method to assist clinicians to identify COVID-19-infected patients by CT images. We collected chest CT scans of 88 patients diagnosed with the COVID-19 from hospitals of two provinces in China, 101 patients infected with bacteria pneumonia, and 86 healthy persons for comparison and modeling. A deep learning-based CT diagnosis system was developed to identify patients with COVID-19. The experimental results showed that our model can accurately identify the COVID-19 patients from the healthy with an AUC of 0.99, recall (sensitivity) of 0.93, and precision of 0.96. When integrating three types of CT images, our model achieved a recall of 0.93 with precision of 0.86 for discriminating COVID-19 patients from others. Moreover, our model could extract main lesion features, especially the ground-glass opacity (GGO) that is visually helpful for assisted diagnoses by doctors. An online server is available for online diagnoses with CT images by http://biomed.nscc-gz.cn/model.php.

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IEEE/ACM Transactions on Computational Biology and Bioinformatics

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This publication has been entered in Griffith Research Online as an advanced online version.

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Mathematical sciences

Biological sciences

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Song, Y; Zheng, S; Li, L; Zhang, X; Zhang, X; Huang, Z; Chen, J; Wang, R; Zhao, H; Zha, Y; Shen, J; Chong, Y; Yang, Y, Deep learning Enables Accurate Diagnosis of Novel Coronavirus (COVID-19) with CT images, IEEE/ACM Transactions on Computational Biology and Bioinformatics, 2021

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