In-air particle generation by on-chip electrohydrodynamics
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Bui, Tung T
Tran, Canh-Dung
Nguyen, Thanh Viet
Nguyen, Tuan-Khoa
Dinh, Toan
Phan, Hoang-Phuong
Wibowo, David
Rehm, Bernd HA
Ta, Hang Thu
Nguyen, Nam-Trung
Dao, Dzung V
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Abstract
Electrohydrodynamic atomization has been emerging as a powerful approach for respiratory treatment, including the generation and delivery of micro/nanoparticles as carriers for drugs and antigens. In this work, we present a new conceptual design in which two nozzles facilitate dual electrospray coexisting with ionic wind at chamfered tips by a direct current power source. Experimental results by a prototype have demonstrated the capability of simultaneously generating-and-delivering a stream of charged reduced particles. The concept can be beneficial to pulmonary nano-medicine delivery since the mist of nanoparticles is migrated without any restriction of either the collector or the assistance of external flow, but is pretty simple in designing and manufacturing devices.
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Lab on a Chip
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© 2021 Royal Society of Chemistry. This is the author-manuscript version of this paper. Reproduced in accordance with the copyright policy of the publisher. Please refer to the journal website for access to the definitive, published version.
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Engineering
Electrical engineering
Nanomaterials
Chemical sciences
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Citation
Dau, VT; Bui, TT; Tran, C-D; Nguyen, TV; Nguyen, T-K; Dinh, T; Phan, H-P; Wibowo, D; Rehm, BHA; Ta, HT; Nguyen, N-T; Dao, DV, In-air particle generation by on-chip electrohydrodynamics, Lab on a Chip, 2021