Topical interventions to prevent acute radiation dermatitis in head and neck cancer patients: a systematic review
File version
Accepted Manuscript (AM)
Author(s)
Vasques, Christiane Inocencio
Gadia, Rafael
Chan, Raymond Javan
Silva Guerra, Eliete Neves
Mezzomo, Luis Andre
Canto, Graziela De Luca
Diniz dos Reis, Paula Elaine
Griffith University Author(s)
Primary Supervisor
Other Supervisors
Editor(s)
Date
Size
File type(s)
Location
License
Abstract
Purpose: The purpose of the study is to evaluate the effects of pharmacological and non-pharmacological topical controls in the prevention of radiation dermatitis. Methods: Relevant clinical trials were identified through electronic searching databases CINAHL, CENTRAL, LILACS, PubMed, Scopus, and Web of Science. Handsearching and gray literature searches were also performed to find additional references. Primary outcomes of interest were the development of radiation dermatitis and the time of occurrence of radiation dermatitis. Results: Thirteen randomized clinical trials were included in this review. The trials were published in Chinese, English, or French, from 1980 to 2015. Pharmacological interventions used in the trials were trolamine, aloe vera, allantoin, Lianbai liquid, sucralfate, Na-sucrose octasulfate, olive oil, hialuronic acid, and dexpanthenol. Non-pharmacological topical controls were usual care/institution routine, aqueous cream, mild soap, water thermal gel, placebo, and no intervention. Conclusions: There was no strong evidence that indicates differences between topical pharmacological interventions or non-pharmacological topical controls in the prevention of acute radiation dermatitis among patients with head and neck cancer undergoing radiotherapy.
Journal Title
Supportive Care in Cancer
Conference Title
Book Title
Edition
Volume
25
Issue
3
Thesis Type
Degree Program
School
Publisher link
Patent number
Funder(s)
Grant identifier(s)
Rights Statement
Rights Statement
© 2017 Springer Berlin/Heidelberg. This is an electronic version of an article published in Supportive Care in Cancer, 2017, 25 (3), pp. 1001-1011. Supportive Care in Cancer is available online at: http://link.springer.com/ with the open URL of your article.
Item Access Status
Note
Access the data
Related item(s)
Subject
Biomedical and clinical sciences
Psychology
Science & Technology
Life Sciences & Biomedicine
Oncology
Health Care Sciences & Services
Rehabilitation
Persistent link to this record
Citation
Ferreira, EB; Vasques, CI; Gadia, R; Chan, RJ; Silva Guerra, EN; Mezzomo, LA; Canto, GDL; Diniz dos Reis, PE, Topical interventions to prevent acute radiation dermatitis in head and neck cancer patients: a systematic review, Supportive Care in Cancer, 2017, 25 (3), pp. 1001-1011