Previous research reported that economic crises may have important implications for increasing suicide rates. We investigated official data on completed suicide in Italy during the recent economic crisis as related to age and gender. Data were extracted from the Italian Mortality Database. The trend in suicide rates from 1980 to 2010 (the most recent year available) was analysed by joinpoint regression analysis. Rate ratios were calculated to compare suicide rates before and after the present economic crisis. Suicide rates for men 25-64 years of age (those involved in the labour force) started to increase in 2008 after a period of a statistically significant decrease from 1994 to 2007 and their suicide rate was 12% higher in 2010 compared with that in 2006. In contrast, suicide rates declined for women of all ages and for men younger than 25 and older than 65 years of age. After 2007, there was a noticeable increase in suicide rates among Italian men involved in the labour force.