CRISPR-Cas system: a potential alternative tool to cope antibiotic resistance
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Rasool, Maria
Idris, Adi
Muzammil, Saima
Alvi, Roman Farooq
Khurshid, Mohsin
Rasool, Muhammad Hidayat
Zhang, Derong
Ma, Zhongren
Baloch, Zulqarnain
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Abstract
Antibiotic exposure leads to massive selective pressures that initiate the emergence and spread of antibiotic resistance in commensal and pathogenic bacteria. The slow process of developing new antibiotics makes this approach counterintuitive for combatting the rapid emergence of new antibiotic resistant pathogens. Therefore, alternative approaches such as, the development of nucleic acid-based anti-bacterial treatments, anti-bacterial peptides, bacteriocins, anti-virulence compounds and bacteriophage therapies should be exploited to cope infections caused by resistant superbugs. In this editorial, we discuss how the newly popular CRISPR-Cas system has been applied to combat antibiotic resistance.
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Antimicrobial Resistance & Infection Control
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9
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1
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© The Author(s). 2020. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made.
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Microbiology
Clinical sciences
Medical microbiology
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Aslam, B; Rasool, M; Idris, A; Muzammil, S; Alvi, RF; Khurshid, M; Rasool, MH; Zhang, D; Ma, Z; Baloch, Z, CRISPR-Cas system: a potential alternative tool to cope antibiotic resistance, Antimicrobial Resistance & Infection Control, 2020, 9 (1)