This paper is focused on optimising the cross-sectional shapes of simply-supported, singly-symmetric and open-section cold-formed steel (CFS) beams and beam-columns without manufacturing or assembly constraints. A previously developed Genetic Algorithm (GA) is used in this study. Fully restrained and unrestrained beams against lateral deflection and twist, as well as unrestrained beam-columns are optimised, of which the nominal member capacities are determined by the Direct Strength Method (DSM). The optimised cross-sectional shapes are presented and the evolution of the unrestrained cross-sectional shapes for various combinations of axial load and bending moment is analysed and discussed.